Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Trauma induced coagulopathy
研究概览
简要总结
The purpose of the study is to find out the incidence of trauma induced coagulopathy in patients with severe trauma who received fibrinogen prior admission to emergency department during prehospital care.
详细描述
The study will commence following the Approval by The Ethics Research Committee. All patients admitted to emergency department during the study will be enrolled after fulfilling the inclusion criteria and in the absence of any exclusion criteria. Informed consent will be requested. After admission to emergency department the blood samples will be taken and blood tests and viscoelastic tests will be performed. All data and results will be entered in the study form. Statistical analysis will be performed and incidence of trauma induced coagulopathy estimated. In addition, 28-day mortality and the incidence of thromboembolic complications will be monitored.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •multiple trauma, injury severity score (ISS) ≥16
- •administration of fibrinogen in prehospital care
- •age 18-80 years
排除标准
- •pregnancy
- •therapeutic anticoagulation
- •therapeutic antiaggregation
结局指标
主要结局
Trauma induced coagulopathy
时间窗: day of enrolment
Incidence of trauma induced coagulopathy
次要结局
- 28day mortality(28 days after enrolment)
- thromboembolic complications(28 days after enrolment)