The effect of jing-well point health exercises on perioperative neurocognitive impairment in elderly patients

Phase 1

• Conditions: perioperative neurocognitive disorders

• Registration Number: ITMCTR2200006802
• Lead Sponsor: Shanghai Fourth People's Hospital affiliated to Tongji University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1) Age 60 years and above;
2) Patients with an estimated anesthesia time of more than 2 hours for elective gastrointestinal surgery;
3) The patients or their families agree to join the study and singe the informed consent form of this study;
4) ASA class I-III.

Exclusion Criteria

1) Patients with central nervous system diseases, including severe cerebrovascular diseases, dementia and mental diseases;
2) Patients with severe liver dysfunction (child Pugh grade C), severe renal insufficiency (dialysis), preoperative left ventricular ejection fraction less than 50%, sick sinus syndrome, severe sinus bradycardia (< 50 beats / min), secondary or greater atrioventricular conduction obstruction without pacemaker;
3)Long-term use of psychotropic drugs
4)History of drug and alcohol abuse (drinking more than 100ml of alcohol with over 40 degrees per day in the past three months)
5)People who have had multiple operationsPatients who had undergone cardiac surgery or craniocerebral surgery within 1 year;
6)Communication problems, such as severe impairment of hearing, vision or speech;
7)The operation lasted more than 3 hours and the intraoperative blood loss exceeded 800 ml;
8)The preoperative MMSE score was less than 24 points;
9)Patients who have participated in other relevant clinical studies within 3 months;
10)The same patient can only be included once, regardless of whether the reason of the second operation is related to the first cause.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Montreal Cognitive Assessment;Mini-mental State Examination;confusion assessment method;

Secondary Outcome Measures

Name	Time	Method
Postoperative hospital stay;CRP;Modified Barthel index;Incidence of postoperative complications;