NL-OMON30619已完成4 期
An open study to investigate the effect of 4 instead of 2 daily dosing mycophenolate mofetil (MMF) in renal transplant patients on diarrhea - 4xMMF
niversitair Medisch Centrum Utrecht0 个研究点目标入组 10 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Male or female > 18 years old
- •Renal transplantation > 6 months with stable renal function (serum creatinine < 250 mumol/L)
- •Use of MMF (Cellcept®) 2 times daily
- •History of diarrhea (> 1 month >= 3 times a day loose/ watery stool in at least 75% of the cases)
- •Willing and capable to give written informed consent
- •Able to communicate and cooperate with the investigators
排除标准
- •Usage of morfinomimetics, anti-diarretics, laxans or other drugs that are known to induce diarrhea.
- •Recent use of antibiotics (< 4 weeks before study)
- •Gastro-intestinal infections (Yersinea, Campylobacter, Shigella, Salmonella, Clostridium difficile toxin, CMV)
- •Known gastro-intestinal diseases or recent major gastro-intestinal surgery
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