Urinary Aquaporin 2 Excretion After NSAID in Fasting Healthy Human
Phase 4
Completed
- Conditions
- Healthy
- Registration Number
- NCT00281762
- Lead Sponsor
- Regional Hospital Holstebro
- Brief Summary
We wanted to test the hypothesis that prostaglandin inhibition reduces the down regulation of u-AQP-2 induced by fasting
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- (1) Genders; both mal and female
- (2) Age; 18- 65 years old
- (3) BMI; below 30
- (4) Females had to bee in oral contraceptive treatment
Exclusion Criteria
- (1) Clinical signs or history of disease in the heart, lungs, kidneys or endocrine organs
- (2) Abnormal laboratory test (blood haemoglobin, white cell count, platelets, plasma sodium, plasma potassium, plasma creatinine, plasma albumin, plasma bilirubin, plasma alanine aminotransferase, plasma cholesterol and blood glucose)
- (3) Albuminuria or glucosuria
- (4) Cancer
- (5) Arterial hypertension
- (6) Alcohol abuse
- (7) Use of tobacco
- (8) Medical treatment, except oral contraceptives
- (9) Pregnancy or breast feeding
- (10) Medicine abuse
- (11) Donation of blood less than 1 month before the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method FeNa U-AQP-2
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Medicine, Holstebro Hospital
🇩🇰Holstebro, Denmark