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Clinical Trials/NCT00358358
NCT00358358
Completed
Phase 4

A Randomized, Double-blind Placebo-controlled Study of Treatments With Salmeterol, Fluticasone Propionate and Their Combination to Evaluate Novel Endpoints in Patients With Chronic Obstructive Pulmonary Disease

GlaxoSmithKline1 site in 1 country163 target enrollmentMarch 2006

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Pulmonary Disease, Chronic Obstructive
Sponsor
GlaxoSmithKline
Enrollment
163
Locations
1
Primary Endpoint
Peripheral airway resistance measured by IOS
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

This study will last for approximately 14 weeks and will involve 5 visits. The study is being carried out to look at different ways of measuring the effect of drug treatment on COPD. COPD is a respiratory disease which can affect your breathing and daily life. Symptoms of COPD can include breathlessness, cough, and wheeze. COPD varies enormously from patient to patient. The effects of drug treatment are usually measured by conducting lung function tests (breathing tests) using a machine called a spirometer but this does not always provide a complete picture of how well your COPD is responding. In this study we therefore want to look at new and more sensitive ways of measuring COPD. The results of this research will help in the assessment of new drugs for COPD in the future.

Detailed Description

Evaluation of Novel Endpoints in Subjects with Chronic Obstructive Pulmonary Disease (COPD) in a Randomized, Double-Blind, Placebo-Controlled Study of Treatment with Fluticasone Propionate/Salmeterol 500/50mcg combination (FSC 500/50) and its individual components, Fluticasone Propionate 500mcg (FP500) and Salmeterol 50mcg (SAL 50)

Registry
clinicaltrials.gov
Start Date
March 2006
End Date
February 2007
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Peripheral airway resistance measured by IOS

Secondary Outcomes

  • Airway wall thickness measured by CT scans

Study Sites (1)

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