Implementation of the New Guidelines on the Management of Patients Resuscitated From Cardiac Arrest and Impact on Survival: a Multicenter Retrospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 693
- 试验地点
- 2
- 主要终点
- Intensive Care Unit (ICU) Survival
研究概览
简要总结
The study aims to evaluate the level of local implementation of the new interventions introduced by the guidelines for post-cardiac arrest management and their impact on the survival of patients resuscitated from cardiac arrest and admitted to intensive care over a 14-year period. During this time period, the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) introduced three new guidelines for post-cardiac arrest management, each five years apart: the 2010, 2015, and 2021 guidelines.
详细描述
This study is a retrospective multicenter cohort observational study (two centers involved: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Fondazione IRCCS San Gerardo dei Tintori).
All patients admitted to the Intensive Care Units (ICU) of the hospitals involved in the study from January 1, 2011, to May 30, 2024, following cardiac arrest of any etiology, who meet the inclusion and exclusion criteria, will be enrolled.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients resuscitated from cardiac arrest and admitted to intensive care unit
- •Age ≥ 18 years
- •Out-of-hospital and in-hospital cardiac arrest
- •Cardiac arrest of any etiology
排除标准
- •Pediatric patients (<18 years)
- •Patients not admitted to one of the aforementioned intensive care units.
结局指标
主要结局
Intensive Care Unit (ICU) Survival
时间窗: From cardiac arrest date to ICU discharge or death, up to 90 days
To evaluate ICU survival for patients resuscitated from cardiac arrest
Neurological recovery at ICU discharge
时间窗: From cardiac arrest date to ICU discharge or death, up to 90 days
ICU Survival with Cerebral Performance Category (CPC) score of 1 or 2
次要结局
- Hospital discharge status(From cardiac arrest date to hospital discharge or death, up to 180 days)
研究者
Mauro Panigada
Medical Doctor, Head of the Intensive Care Unit, Department of Anaesthesia, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan
Policlinico Hospital