Effects of wholegrain-derived compounds supplementation on blood vessel stiffness

Not Applicable

Completed

• Conditions: Blood pressure; Circulatory System

• Registration Number: ISRCTN11698069
• Lead Sponsor: The University of Aberdeen

Brief Summary

2017 thesis in https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737946 (added 23/04/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-04-04
• Study Completion: 2018-09-01
• Last Update Posted: 3 May 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 25

Inclusion Criteria

1. Male
2. Aged 40-65 years old
3. 115mmHg = systolic blood pressure =159mmHg & 70mmHg = diastolic blood pressure = 99mmHg
4. BMI between 19 and 30 kg/m2

Exclusion Criteria

1. BMI under 19 kg/m2 or over 30kg/m2
2. Systolic blood pressure >159mmHg or <115mmHg & diastolic blood pressure
3. Any pharmalogical treatment for hypertension or depression
4. Suffering from eating disorders and/or taking any nutritional supplements, and/or usually eating high intake of wholegrains or probiotics

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arterial function measured by pulse wave analysis

Secondary Outcome Measures

Name	Time	Method
<br> 1. Blood pressure measured using the 24 hour blood pressure monitor over the 24 hours following each of the two study visits<br> 2. Systemic markers of endothelial function<br> 3. Blood pressure regulation<br>