NL-OMON38291
已完成
不适用
Structural brain changes in bipolar disorder - Structural brain changes in bipolar disorder
niversitair Medisch Centrum Utrecht0 个研究点目标入组 600 人待定
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- bipolar disorder
- 发起方
- niversitair Medisch Centrum Utrecht
- 入组人数
- 600
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Patients with bipolar disorder
- •\- A diagnosis of BD\-I according to the DSM IV, with at least one clinical intervention for mania (DSM\-IV criteria)
- •\- No history of Cognitive Disorder (DSM\-IV criteria)
- •\- Age \>\= 18 years
- •\- Dutch ancestry (at least three of the four grandparents from the Netherlands);Healthy controls
- •\- Age \>\= 18 years
- •\- Dutch ancestry (at least three of the four grandparents from the Netherlands)
- •\- No history of bipolar disorder, schizophrenia or other psychotic disorder (DSM\-IV criteria)
- •\- No first degree relative with a history of bipolar disorder, schizophrenia or other psychotic disorders (DSM\-IV criteria), on the basis of a FIGS interview
排除标准
- •\- Premorbid IQ \< 80
- •\- Did not give written informed consent
- •\- Ferrous objects in or around the body
- •\- Drug or alcohol abuse over a period of six months prior to the experiment (DSM\-IV criteria)
- •\- History of closed\-head injury
- •\- History of neurological illness or endocrinological dysfunction
- •\- Claustrophobia
- •\- Severe medical illness
- •\- Current treatment or detention under the Dutch governmental mental health act.
- •\- Participants that cannot read, speak or understand Dutch.
结局指标
主要结局
未指定
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