NL-OMON30080
撤回
不适用
Brain morphology in bipolar twin pairs compared with healthy control twin pairs - Follow up - BrABiT: Brain Anatomy in Bipolar Twins
niversitair Medisch Centrum Utrecht0 个研究点目标入组 220 人待定
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- niversitair Medisch Centrum Utrecht
- 入组人数
- 220
- 状态
- 撤回
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •1\) Part of a monozygotic or dizygotic twin pair
- •2\) For monozygotic twin pairs at least one twin (MZ concordant and MZ discordant) and for dizygotic twin pairs only one twin (DZ discordant) has a diagnoses (life time):
- •\- Bipolar Disorder I or Bipolar Disorder II (DSM\-IV criteria)
- •\- For the interview and blood sample: not in a acute (hypo)manic or major depressive episode
- •3\) Age between 18 and 60 years;Healthy controls:
- •1\) Part of a monozygotic or same\-sex dizygotic twin pair
- •2\) Matched to patient groups on age, sex and zygosity
- •3\) Age between 18 and 60 years
排除标准
- •1\) No history of drug or alcohol dependency (DSM\-IV criteria) for the last half year
- •2\) No history of Cognitive Disorder (DSM\-IV criteria)
- •3\) No history of serious neurological illness
- •4\) No severe medical illness
- •Healthy controls:
- •1\) No history of specific axis I psychiatric disorder (DSM\-IV criteria), on the basis of a SCID interview (Modules A\-G)
- •2\) No history of axis II personality disorder (DSM\-IV criteria), on the basis of SIDP\-V
- •3\) No first degree relative with a history of specific axis I psychiatric disorder (DSM\-IV criteria), on the basis of a FIGS interview
- •4\) No history of serious neurological illness
- •5\) No severe medical illness
结局指标
主要结局
未指定
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