The impact of dancing versus health-related physical exercise on structural neuroplasticity, working memory and selected cognitive and motor functions in senior citizen.
Not Applicable
- Conditions
- healthy elderly
- Registration Number
- DRKS00012605
- Lead Sponsor
- Deutsches Zentrum für Neurodegenerative Erkrankungen (Helmholtz Gemeinschaft)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 57
Inclusion Criteria
mental health (MMSE > 27 points), no physical or health issues
Exclusion Criteria
Metalic implants, neurologic diseases, regular physical training (>1/week), tattoos, claustophobia, tinnitus, depressive symptoms (BDI-II)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Structural changes in gray and white matter volume:<br><br>Structural data were assessed using 3T MRI and analysed using VBM (voxel based morphometry) (SPM12) and DTI (Diffusions-Tensor Imaging).<br><br>2. Investigation in changes of BDNF-Level (Brain-Derived-Neurotrophic Factor):<br><br>Blood samples were taken under fast conditions and analysed regarding the neurotrophin BDNF.<br><br>3. Cognitive Testing:<br>Testbattery to assess Attention (TAP), verbal learn and memory test (VLMT), Rey-Osterrieth-Complex-Figure Test (ROCFT), Mini Mental Status Examination (MMSE), Verbal word fluency test, Wechsler Memory Scale-R (Number Span forward and backward), Trail-Making Test (German Version:ZVT), CANTAB<br><br>3. Physical Testing:<br>motor sequence leraning test, Physical Working Capacity 130, Spatial Navigation Test, Balnace Test (Sensory Organisation Test and Limits of Stability)<br><br>Basline: June 2012 - September 2012<br>Post-test: April 2013 - June 2013
- Secondary Outcome Measures
Name Time Method Questionnaire for Biography of Physical Activity (Wollny, 2002) throughout the life span (childhood, youth, young, middle and late adulthood)<br><br>Screeings-Assessments to exclude/include subjects:<br>- Mini Mental Status Examination (Folstein et al., 1990) to assess cognitive health<br>- Becks-Depression-Iventory II<br>- Freiburger Questionnaire for Physical Activity<br>- Heath Questionnaire to assess neurologic or other diseases, medical treatments, physical activity.<br><br>During the intervention we used a questionnaire to assess daily activity and the sleep-behavior (IPAQ - International Physical Activity Questionnaire)<br>