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临床试验/CTRI/2025/07/091488
CTRI/2025/07/091488尚未招募4 期

Comparison of Analgesic Efficacy of USG Guided External Oblique Intercostal Plane block vs Subcostal Transversus Abdominis Plane Block in Patients Undergoing Elective Laparoscopic Cholecystectomy Randomised Controlled Trial

Ballari Medical College and Research Centre Ballari1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2025年8月14日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
48
试验地点
1
主要终点
To compare time to first rescue analgesia between External oblique intercostal plane block and subcostal Transversus abdominis plane block in patients undergoing laparoscopic cholecystectomy

研究概览

简要总结

Title

"COMPARISON OF ANALGESIC EFFICACY OF USG GUIDED EXTERNAL OBLIQUE INTERCOSTAL PLANE BLOCK VS SUBCOSTAL TRANSVERSUS ABDOMINIS PLANE BLOCK IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY: RANDOMISED CONTROLLED STUDY"

Need for Study/Introduction

Laparoscopically performed Cholecystectomy is the corner stone of modern surgical practice as it speeds up post operative recovery. Even if LC is a minimally invasive procedure, patients may experience severe pain the postoperative period. Such pain can occur due to inflammation as result of surgical trauma, muscle and soft tissue trauma caused by port entry sites, insufflation of the abdominal cavity with carbon dioxide and trauma to the liver caused by dissection of the gall bladder. Inadequate analgesia in LC has implications for post operative pain management and patient recovery, as it can lead to delayed mobilization and a longer hospitalization period. In our institution we use inj. Fentanyl 2 mcg/kg, inj. Paracetamol 15 mg/kg IV infusion, local port site infiltration for analgesia. PROSPECT guidelines recommend truncal blocks for post-LC analgesia Regional anaesthesia technique have increasingly become essential components of multimodal analgesia, providing targeted pain relief while minimizing systemic opioid requirements.

Despite promising preliminary data, there remains a paucity of direct comparative studies evaluating the efficacy of EOIP versus TAP blocks in Laparoscopic Cholecystectomy surgeries. A rigorous assessment of these two techniques is necessary to determine the most effective and reliable regional block for optimizing postoperative pain control in this patient population

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • All patients who will be under going elective laparoscopic cholecystectomy done under general anaesthesia ASA 1 and 2 between 18 t0 60 years.

排除标准

  • Patient refusal for procedure Patients with derange coagulation profile Patient with puncture site infection History of allergy to local anesthetic/study drugs Neuromuscular diseases.

结局指标

主要结局

To compare time to first rescue analgesia between External oblique intercostal plane block and subcostal Transversus abdominis plane block in patients undergoing laparoscopic cholecystectomy

时间窗: Duration of post operative analgesia after 4 hours, 8 hours, 12 hours,18 hours, 24 hours

次要结局

  • To evaluate and compare postoperative pain scores between patients receiving EOIP block and those receiving TAP block at various time intervals.(The amount of Tramadol consumption in the first 24 post operative hours.)

研究者

发起方
Ballari Medical College and Research Centre Ballari
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Akhil Kumar G

Ballari Medical College and Research Centre

研究点 (1)

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