Effect of magnesium sulphate on total amount of muscle relaxant required to conduct deep and moderate neuromuscular block surgeries and the effect of magnesium sulphate on total amount of fentanyl required to releive postoperative pain after these surgeries.
Phase 4
- Conditions
- Health Condition 1: K800- Calculus of gallbladder with acutecholecystitisHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2021/02/031434
- Lead Sponsor
- ANUREET KAUR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)ASA grade 1,2,3
2)Patients aged between 18 to 60 years
3)BMI <35 Kg/m2
4)Patients scheduled for laproscopic cholecystectomy under General Anaesthesia
Exclusion Criteria
1)Patient refusal to give consent
2)Patients with known hypersensitivity to magnesium and cis Atracurium
3)Pregnant patients
4)Patients with history of abdominal surgery
5)Patients with major organ dysfunction
6)Patients using any hypnotics or analgesic
7)Patients having neuromuscular disease that may interfere with neuromuscular function
8)Patients receiving medications known to influence neuromuscular function(eg. calcium channel blockers, phenytoin and aminoglycosides)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To calculate and compare total cisatracurium consumption in deep and moderate neuromuscular blockade groups with and without magnesium sulphateTimepoint: After intubation of patient, at 5 minutes , 10 minutes , 15 minutes , 20 minutes , 25 minutes, 30 minutes , 35 minutes , 40 minutes , 2 hours, 6 hours, 12 hours.
- Secondary Outcome Measures
Name Time Method To calculate Minimum effective analgesic dose of fentanyl in post anaesthesi care unit, mean VAS score at rest, on movement and on wound compressionTimepoint: 2 hr, 6 hr, 12 hr after surgery