To detect a better adjuvant between magnesium sulphate and lignocaine for pretreatment with rocuronium
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/04/066229
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American Society Of Anaesthesiologist (ASA) grading 1-2
2. BMI 18.5-29.9
3. All GA Surgeries lasting for more than 2 hrs
Exclusion Criteria
1.Refused To Participate In The Study
2.Cardiac Conduction Abnormalities
3.Patients Having Neuromuscular Disease
4.known hepatic and renal dysfunction
5.Allergies to study drugs
6.Patients having electrolyte abnormalities
7.Patients on medications known to alter neuromuscular function
8.Patients having expected difficult mask ventilation or difficult laryngoscopy and intubation
9.Pregnant women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ONSET OF NEUROMUSCULAR BLOCKADE OF ROCURONIUMTimepoint: From the time of giving rocurnium to the time of achieving T1(first twitch) less than or equal to 5%
- Secondary Outcome Measures
Name Time Method HEMODYNAMIC RESPONSE TO LARYNGOSCOPYTimepoint: Just before intubation, during laryngoscopy, just after intubation, 5 mins after intubation;time of first top-up dose of rocuroniumTimepoint: TOF Count 2-3;Time of neuromuscular recoveryTimepoint: TOF ratio more than or equal to 0.9;Total cumulative dose of RocuroniumTimepoint: At the end of last top-up dose