ongitudinal cohort study to investigate long-term medical and psychosocial outcomes of physical battlefield trauma casualties

Defence Medical Services, MoD0 个研究点目标入组 1,145 人开始时间: 2019年11月18日最近更新: 2024年4月8日

适应症

试验速览

2022 Interim results article in https://pubmed.ncbi.nlm.nih.gov/35717965/ (added 20/06/2022) 2024 Other publications in https://doi.org/10.1016/j.bja.2024.02.019 Pain after combat injury in male UK military personnel deployed to Afghanistan (added 25/03/2024)

•Exposed Group:
•1. UK Armed services personnel
•3. Sustained physical battlefield trauma, while on deployment in Operation Herrick (Afghanistan), requiring aeromedical evacuation and direct UK hospital admission
•4. Injured during 2003 or after
•Non-Exposed Group:
•1. UK Armed services personnel
•3. Previously deployed
•4. No battlefield trauma, as defined in the inclusion criteria

•1. Unwilling or unable to give informed consent
•2. Established CVD (previous stroke or transient ischaemic attack [TIA], ischaemic heart disease [IHD], peripheral vascular disease)
•3. Past medical history of diabetes
•4. Past medical history of renal or liver disease
•5. Aged <18 and >50 years
•6. Active acute infection with systemic features of sepsis, at the time of first visit, as defined below. Potential participant with active acute infection will be considered for recruitment once the acute illness is treated and resolved
•7. Two of three of:
•7.1. Temperature >38ºC or <36ºC
•7.2. Heart rate >90beats/min
•7.3. Respiratory rate >20 breaths/min

发起方

Defence Medical Services, MoD