Transnasal direct cholangioscopy (TDC) with ultra-slim endoscopes: feasibility for diagnosis and therapy of cholangiopathies

Not Applicable

• Conditions: C22.1; K80; Intrahepatic bile duct carcinoma; Cholelithiasis

• Registration Number: DRKS00000626
• Lead Sponsor: Dr. Horst-Schmidt-Klinik Wiesbaden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12-03
• Study Completion: 2012-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Follow-up after stone removal
Evaluation of biliary stricture
Adenomas of the papilla with suspected ductal involvement
Removal of retained common bile duct stones A previous endoscopic sphincterotomy was a prerequisite for inclusion.

Exclusion Criteria

Patients with a diffuse stricture of the distal common bile duct
bleeding tendency (international normalized ratio > 1.5 or platelet count < 50,000/mL)
Patients with evidence of pancreatic cancer
Patients with surgical altered anatomy
Patients with contraindications for ERCP were excluded.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome is the technical success rate, defined as successful advancement of the endoscope into the bifurcation of the biliary tree or the strictured segment.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are :<br>1. Complications, such as perforation, cholangitis, pancreatitis, and bleeding. <br>2. Success rate of therapeutic procedures (e.g. lithotripsy, argon plasma coagulation).<br>