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Clinical Trials/NCT05994820
NCT05994820
Completed
Not Applicable

Implementing and Evaluating a Chatbot-based Intervention to Promote Vaccine Acceptance in Varansi, India

Johns Hopkins Bloomberg School of Public Health1 site in 1 country2,058 target enrollmentSeptember 26, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Vaccine Hesitancy
Sponsor
Johns Hopkins Bloomberg School of Public Health
Enrollment
2058
Locations
1
Primary Endpoint
Post Intervention Vaccine Attitudes
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to learn compare the efficacy Chatbot messaging directed to parents of infants and children living in unstable urban housing (UUH) in Varansi, India. The main questions it aims to answer are: 1) Can a Chatbot intervention be used to improve attitudes towards childhood vaccines? 2) Does an intervention in which vaccination is presented in the larger context of well-being improve attitudes towards vaccination?

Detailed Description

Only 2/3 of Indian infants and children are fully immunized. In communities facing unstable urban housing (UUH) vaccination rates are even lower. COVID-19 introduced new challenges for community health workers in these areas, and many do not have the capacity to promote vaccination. At the same time, the pandemic also prompted more parents and caregivers to engage with smartphones to manage the child's health. The investigators believe that a WhatsApp-based Chatbot intervention may be an effective way to promote routine childhood vaccination among caregivers without creating additional burdens on community health workers. To test this, the investigators are developing the Happy Baby Programme. This programme will be disseminated as a Chatbot through WhatsApp to parents of infants and young children living in Varanasi, in the Indian state of Uttar Pradesh. In addition to testing the overall efficacy of a Chatbot messaging platform, the investigators will compare two different Chatbot messaging designs, one featuring vaccine-only messaging and a second that positions vaccines as part of a broader set of well-being practices.

Registry
clinicaltrials.gov
Start Date
September 26, 2023
End Date
February 10, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Speak Hindi;
  • Reside in selected UUH neighborhood of Varanasi, India;
  • Identify as a caregiver of a young child (\<2) OR be at least 5 months pregnant and due to giver birth during the study period;
  • Child is registered with local community health workers and included on patient rosters for vaccination clinics (also known as Village Health Sanitation and Nutrition Days (VHSNDs));
  • Have regular access to a phone with WhatsApp.

Exclusion Criteria

  • Only one caregiver is eligible per household
  • Not meeting inclusion criteria.

Outcomes

Primary Outcomes

Post Intervention Vaccine Attitudes

Time Frame: 4 months

Vaccine attitudes will be assessed through an 8-item scale using Likert-style questions that ask participants to respond on a five-point scale (from strongly disagree to strongly agree, where higher scores mean more positive agreement). Responses will be averaged into an index (spanning from 0 = lowest intention to 5 = highest intention to vaccinate) to signify vaccine attitudes. We will assess changes in these attitudes from baseline to post-intervention. Please note that, in this methodology, there is no need to create a binary "negative attitude" versus "positive attitude."

Post Intervention Vaccine Intentions

Time Frame: 4 months

Vaccine intentions will be assessed through 3-Likert type questions that ask participants to respond on a five-point scale (from strongly disagree to strongly agree, where higher scores mean more higher intentions). Responses will be averaged into an index (spanning from 0 = lowest intention to 5 = highest intention to vaccinate) to signify vaccine intentions. We will assess changes in these intentions from baseline to post-intervention.

Post Intervention Vaccine Hesitancy

Time Frame: 4 months

Vaccine Hesitancy will be assessed through a validated 10-item scale from Shapiro et al. 2017. All items utilize a Likert-type response format. that ask participants to respond on a five-point scale (from strongly disagree to strongly agree, where higher scores mean more positive agreement) answers. Responses will be averaged into an index (spanning from 0 = most hesitancy, to 5 = least least hesitancy) to signify vaccine hesitancy. We will assess changes in hesitancy from baseline to post-intervention. Please note that, in this methodology, there is no need to create a binary "hesitant" versus "not hesitant."

Secondary Outcomes

  • Parental Awareness of Vaccine Services(4 months)

Study Sites (1)

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