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A Study of Smoking Cessation Patterns in Participants Undergoing Lung Surgery

Completed
Conditions
Lung Neoplasms
Pulmonary Disease, Chronic Obstructive
Interventions
Other: No intervention
Registration Number
NCT04313361
Lead Sponsor
Johnson & Johnson (China) Investment Ltd.
Brief Summary

The purpose of this study is to assess the current smoking status and smoking cessation attempts among smokers or recent smoking quitters during the perioperative period, to describe postoperative pulmonary complications (PPCs) and other postoperative complications (PCs) following a lung surgery, and to describe the smoking cessation methods and services patients received from their health care professionals (HCPs) and participant's satisfaction among participants with lung cancer, chronic obstructive pulmonary disorder (COPD), a pulmonary lesion (example, nodule, or ground glass opacity) or other pulmonary conditions who are admitted to the thoracic surgical unit of the participating hospitals in China.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
290
Inclusion Criteria
  • Participants who have been scheduled for an elective lung surgery by the treating physician's judgement, due to the following conditions: known lung cancer, COPD, a pulmonary lesion (example. nodule, ground glass opacity) or other pulmonary conditions
  • Smokers who are or were smoking on average no fewer than 5 cigarettes per day for equal or more than 3 years within 3 months prior to the scheduled surgery, or recent smoking quitters with a history of smoking on average no fewer than 5 cigarettes per day for equal or more than 3 years, who quit smoking between 3 months and 5 years prior to the scheduled surgery
  • Being willing to participate the study and sign the participant informed consent form (ICF)
Exclusion Criteria
  • Participants who have emergency lung surgery due to accident or injury
  • Participants are not likely to be able to complete the 6-month follow-up after the lung surgery

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Smokers or Recent Smoking Quitters who Have lung SurgeryNo interventionThe enrolled eligible participants, that is smokers or recent smoking quitters, will be assessed for the current smoking status and smoking cessation attempts during the perioperative period, to describe postoperative complications (PCs) including postoperative pulmonary complications (PPCs) following a lung surgery, and to describe the smoking cessation methods and services participants received from their health care professionals (HCPs) and participant's satisfaction among participants with lung cancer, chronic obstructive pulmonary disorder (COPD), a pulmonary lesion (example nodule, ground glass opacity) or other pulmonary conditions who are admitted to the thoracic surgical unit of the participating hospitals in China.
Primary Outcome Measures
NameTimeMethod
Percentage of Smokers and Recent Smoking Quitters at Baseline Prior to the SurgeryBaseline Prior to the Surgery

Percentage of smokers and recent smoking quitters at baseline prior to the surgery will be reported.

Percentage of Participants Using NRTs at Month 3 Post-surgeryMonth 3 post-surgery

Percentage of participants using NRTs, types of NRTs used and perceived effectiveness, at Month 3 post surgery will be reported.

Percentage of Participants with Smoking Relapse at Month 3 Post-surgeryMonth 3 post-surgery

Percentage of participants with smoking relapse at Month 3 post-surgery will be reported.

Smoking Dependence Among Smokers as Measured by Fagerstrom Test of Nicotine Dependence (FTND) Scale at Baseline Prior to the SurgeryBaseline Prior to the Surgery

Level of smoking dependence will be measured by FTND Scale in the participant's questionnaire. FTND is a 6-item self-report measure of nicotine dependence derived from the Fagerström Tolerance Questionnaire, which comprises yes/no options (scored from 0 to 1) and multiple-choice items (scored from 0 to 3). The items are summed to yield a total score of 0-10. The higher the total Fagerström score, the more intense is the participant's physical dependence on nicotine.

Number of Smoking Cessation Attempts at Baseline Prior to the SurgeryBaseline prior to the surgery

Number of smoking cessation attempts at baseline prior to the surgery will be reported.

Percentage of Participants Using NRTs, Types of NRTs Used and Perceived Effectiveness at Month 6 Post-surgeryMonth 6 post-surgery

Percentage of participants using NRTs, types of NRTs used and perceived effectiveness, at Month 6 post surgery will be reported.

Smoking Dependence Among Smokers as Measured by FTND Scaleat Month 3 Post-surgeryMonth 3 post-surgery

Level of smoking dependence will be measured by FTND Scale in the participant's questionnaire. FTND is a 6-item self-report measure of nicotine dependence derived from the Fagerström Tolerance Questionnaire, which comprises yes/no options (scored from 0 to 1) and multiple-choice items (scored from 0 to 3). The items are summed to yield a total score of 0-10. The higher the total Fagerström score, the more intense is the participant's physical dependence on nicotine.

Smoking Dependence Among Smokers as Measured by FTND Scaleat Month 6 Post-surgeryMonth 6 post-surgery

Level of smoking dependence will be measured by FTND Scale in the participant's questionnaire. FTND is a 6-item self-report measure of nicotine dependence derived from the Fagerström Tolerance Questionnaire, which comprises yes/no options (scored from 0 to 1) and multiple-choice items (scored from 0 to 3). The items are summed to yield a total score of 0-10. The higher the total Fagerström score, the more intense is the participant's physical dependence on nicotine.

Number of Smoking Cessation Attempts at Month 1 Post-surgeryMonth 1 post-surgery

Number of smoking cessation attempts at Month 1 post-surgery will be reported.

Percentage of Participants Using NRTs at Month 1 Post-surgeryMonth 1 post-surgery

Percentage of participants using NRTs, types of NRTs used and perceived effectiveness, at Month 1 post surgery will be reported.

Smoking Dependence Among Smokers as Measured by FTND Scale at Month 1 Post-surgeryMonth 1 post-surgery

Level of smoking dependence will be measured by FTND Scale in the participant's questionnaire. FTND is a 6-item self-report measure of nicotine dependence derived from the Fagerström Tolerance Questionnaire, which comprises yes/no options (scored from 0 to 1) and multiple-choice items (scored from 0 to 3). The items are summed to yield a total score of 0-10. The higher the total Fagerström score, the more intense is the participant's physical dependence on nicotine.

Percentage of Participants Using Nicotine Replacement Therapy (NRTs) at Baseline Prior to SurgeryBaseline prior to surgery

Percentage of participants using NRTs, types of NRTs used and perceived effectiveness, at baseline prior to surgery will be reported.

Percentage of Participants with Smoking Relapse at Month 1 Post-surgeryMonth 1 post-surgery

Percentage of participants with smoking relapse at Month 1 post-surgery will be reported.

Percentage of Participant's Satisfaction on the Smoking Cessation Methods Received from HCPs at Month 6 Post-surgeryMonth 6 post-surgery

Percentage of participant's satisfaction on the smoking cessation methods received from HCPs at Month 6 post-surgery will be reported.

Number of Smoking Cessation Attempts at Month 3 Post-surgeryMonth 3 post-surgery

Number of smoking cessation attempts at Month 3 post-surgery will be reported.

Percentage of Participants with Self-reported Smoking Abstinence and Point Prevalence at Month 6 Post-surgeryMonth 6 post-surgery

Percentage of participants with self-reported smoking abstinence and point prevalence of smoking at Month 6 post-surgery will be reported.

Percentage of Participants with Smoking Relapse at Month 6 Post-surgeryMonth 6 post-surgery

Percentage of participants with smoking relapse at Month 6 post-surgery will be reported.

Overall Incidence of PCs and PPCs Post-surgery (Within 6 Months Post-surgery) and by Baseline Smoking StatusWithin 6 months post-surgery

Overall incidence of PCs and PPCs post-surgery (within 6 months post-surgery) and by baseline smoking status will be reported.

Percentage of Participants who Received Advice from HCPs to Quit Smoking at Baseline Prior to SurgeryBaseline prior to surgery

Percentage of participants who received advice from HCPs to quit smoking at baseline prior to surgery will be reported.

Percentage of Specific Smoking Cessation Methods and Service Participants Received from HCPs at Month 6 post-surgeryMonth 6 post-surgery

Percentage of specific smoking cessation methods and service participants received from HCPs at Month 6 post-surgery will be reported.

Number of Smoking Cessation Attempts at Month 6 Post-surgeryMonth 6 post-surgery

Number of smoking cessation attempts at Month 6 post-surgery will be reported.

Number of Participants who Used Methods and Medications for Smoking Cessation at BaselineBaseline

Number of participants who used prior methods and medications for smoking cessation at baseline will be reported.

Number of Participants who Used Current Methods and Medications for Smoking Cessation at Month 1 Post-surgeryMonth 1 post-surgery

Number of participants who used current methods or medication for smoking cessation at Month 1 post-surgery will be reported.

Number of Participants who Used Current Methods and Medications for Smoking Cessation at Month 3 Post-surgeryMonth 3 post-surgery

Number of participants who used current methods or medication for smoking cessation at Month 3 post-surgery will be reported.

Number of Participants who Used Prior Methods and Medications for Smoking Cessation at Month 6 Post-surgeryMonth 6 post-surgery

Number of participants who used current methods or medication for smoking cessation at Month 6 post-surgery will be reported.

Percentage of Participants with Self-reported Smoking Abstinence and Point Prevalence at Month 1 Post-surgeryMonth 1 post-surgery

Percentage of participants with self-reported smoking abstinence and 7-days/30-day point prevalence of smoking at Month 1 post-surgery will be reported.

Percentage of Participants with Self-reported Smoking Abstinence and Point Prevalence at Month 3 Post-surgeryMonth 3 post-surgery

Percentage of participants with self-reported smoking abstinence and point prevalence of smoking at Month 3 post-surgery will be reported.

Overall Incidence of PCs and PPCs Post-surgery (Within 2 Weeks After Surgery) and by Baseline Smoking StatusWithin 2 weeks after surgery

Overall incidence of PCs and PPCs post-surgery (within 2 weeks after surgery) and by baseline smoking status will be reported.

Percentage of Participants who Received Advice from HCPs to Quit Smoking at Month 3 post-surgeryMonth 3 post-surgery

Percentage of participants who received advice from HCPs to quit smoking at Month 3 post-surgery will be reported.

Percentage of Participants who Received Advice from HCPs to Quit Smoking at Month 6 post-surgeryMonth 6 post-surgery

Percentage of participants who received advice from HCPs to quit smoking at Month 6 post-surgery will be reported.

Percentage of Specific Smoking Cessation Methods and Service Participants Received from HCPs at Month 3 post-surgeryMonth 3 post-surgery

Percentage of specific smoking cessation methods and service participants received from HCPs at Month 3 post-surgery will be reported.

Overall Incidence of Postoperative Complications (PCs) and Postoperative Pulmonary Complications (PPCs) Post-surgery (at 1 Day Prior to Discharge)and by Baseline Smoking StatusAt 1 day prior to discharge

Overall incidence of PCs and PPCs post-surgery (at 1 day prior to discharge) and by baseline smoking status will be reported.

Overall Incidence of PCs and PPCs Post-surgery (Within 3 Months Post-surgery) and by Baseline Smoking StatusWithin 3 months post-surgery

Overall incidence of PCs and PPCs post-surgery (within 3 months post-surgery) and by baseline smoking status will be reported.

Percentage of Participants who Received Advice from HCPs to Quit Smoking at Month 1 Post-surgeryMonth 1 post-surgery

Percentage of participants who received advice from HCPs to quit smoking at Month 1 post-surgery will be reported.

Percentage of Specific Smoking Cessation Methods and Service Participants Received from HCPs at Baseline Prior to SurgeryMonth 1 post-surgery

Percentage of specific smoking cessation methods and service participants received from HCPs at Month 1 post-surgery will be reported.

Percentage of Participant's Satisfaction on the Smoking Cessation Methods Received from HCPs at Baseline Prior to SurgeryBaseline prior to surgery

Percentage of participant's satisfaction on the smoking cessation methods received from HCPs at baseline prior to surgery will be reported.

Overall Incidence of PCs and PPCs Post-surgery (Within 1 Month Post-surgery) and by Baseline Smoking StatusWithin 1 month post-surgery

Overall incidence of PCs and PPCs post-surgery (within 1 month post-surgery) and by baseline smoking status will be reported.

Percentage of Participant's Satisfaction on the Smoking Cessation Methods Received from HCPs at Month 1 Post-surgeryMonth 1 post-surgery

Percentage of participant's satisfaction on the smoking cessation methods received from HCPs at Month 1 post-surgery will be reported.

Percentage of Participant's Satisfaction on the Smoking Cessation Methods Received from HCPs at Month 3 Post-surgeryMonth 3 post-surgery

Percentage of participant's satisfaction on the smoking cessation methods received from HCPs at Month 3 post-surgery will be reported.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (3)

Xuanwu Hospital ,Capital Medical University

🇨🇳

Beijing, China

Ruijin Hospital Shanghai Jiao Tong University

🇨🇳

Shanghai, China

The First Affiliated Hospital of Guangzhou Medical University

🇨🇳

Guangzhou, China

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