Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes: A Matched Cohort Study Using the NSQIP Database
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Renal Insufficiency
- Sponsor
- Taipei Medical University Hospital
- Enrollment
- 2421286
- Locations
- 1
- Primary Endpoint
- Risk of postoperative mortality
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The main purpose of this study is to evaluate the risk of postoperative mortality and complications in surgical populations with preoperative renal insufficiency.
Detailed Description
This retrospective cohort study use the National Surgical Quality Improvement Program (NSQIP) database to evaluate the risk of postoperative morbidity and mortality in the surgical population. Patients with estimated. glomerular filtration rate(GFR) \< 60 ml/min per 1.73 square meter are defined as the renal insufficiency group. Patients with estimated GFR \> 90 ml/min per 1.73 square meter are defined as patients without renal insufficiency. Propensity score-matching methods and multivariate logistic regression are used to calculate the risk of postoperative morbidity and mortality.
Investigators
Chao-Shun Lin
principal investigator
Taipei Medical University Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients with estimated GFR \< 60 ml/min per 1.73 square meter or currently on dialysis are included in renal insufficiency group.
- •Patients with estimated GFR \> 90 ml/min per 1.73 square meter are included in non-renal insufficiency group
Exclusion Criteria
- •Patients population with estimated GFR between 60-90 is not included in the study
Outcomes
Primary Outcomes
Risk of postoperative mortality
Time Frame: 30 days after surgery date
Calculate risk of postoperative 30-day in-hospital mortality between groups
Secondary Outcomes
- Risk of postoperative morbidities(30 days after surgery date)