Preoperative Renal Insufficiency Predicts Postoperative Adverse Outcomes: A Matched Cohort Study Using the NSQIP Database
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,421,286
- 试验地点
- 1
- 主要终点
- Risk of postoperative mortality
研究概览
简要总结
The main purpose of this study is to evaluate the risk of postoperative mortality and complications in surgical populations with preoperative renal insufficiency.
详细描述
This retrospective cohort study use the National Surgical Quality Improvement Program (NSQIP) database to evaluate the risk of postoperative morbidity and mortality in the surgical population. Patients with estimated. glomerular filtration rate(GFR) < 60 ml/min per 1.73 square meter are defined as the renal insufficiency group. Patients with estimated GFR > 90 ml/min per 1.73 square meter are defined as patients without renal insufficiency. Propensity score-matching methods and multivariate logistic regression are used to calculate the risk of postoperative morbidity and mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with estimated GFR < 60 ml/min per 1.73 square meter or currently on dialysis are included in renal insufficiency group.
- •Patients with estimated GFR > 90 ml/min per 1.73 square meter are included in non-renal insufficiency group
排除标准
- •Patients population with estimated GFR between 60-90 is not included in the study
结局指标
主要结局
Risk of postoperative mortality
时间窗: 30 days after surgery date
Calculate risk of postoperative 30-day in-hospital mortality between groups
次要结局
- Risk of postoperative morbidities(30 days after surgery date)
研究者
Chao-Shun Lin
principal investigator
Taipei Medical University Hospital