Upper Cervical and Thoracic Chiropractic Adjustment

Not Applicable

Suspended

• Conditions: Stress
• Interventions: Procedure: Upper Cervical Adjustemnt; Procedure: Thoracic Adjustemnt

• Registration Number: NCT05465395
• Lead Sponsor: Life University

Brief Summary

The proposed study examines the differences in how the ANS responds to cervical adjustments in comparison to thoracic adjustments. This study is the continuation of a previous study titled Perceived stress and patterns of autonomic function: a protocol development study. Autonomic tests such as HRV, GSR, and the stress surveys will be the primary method of measurement. CareTaker and Biopac devices will provide continual data collection of ECG (for HRV analysis) and GSR throughout the exam and adjustment. Participant's subjective stress levels will be measured through the use of stress questionnaires including the National Stressful Events Survey Acute Stress Disorder Short Scale, the Hamilton Anxiety Rating Scale, and the Connor-Davidson Resilience Scale. The objective of the study is to determine if the location of a chiropractic adjustment will affect the autonomic nervous system in such a way that PNS or SNS activation increases or decreases after the adjustment. Further, the study will continue to examine how the chiropractic adjustment affects the subjective stress response.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-12
• Study First Submitted: 2022-03-07
• Study First Submitted QC: 2022-07-15
• Study First Posted: 2022-07-19
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-01
• Last Update Posted: 2023-05-03
• Primary Completion: 2023-11-01
• Study Completion: 2023-11-01

Recruitment & Eligibility

• Status: SUSPENDED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Over the age of 19
• In good health
• Willing to have blood pressure taken
• Willinig to shave a small area of chest hair for placement of a ECG patch
• Consent to a physical exam
• Consent ot chiropractic evaluationa nd 2 adjustments

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Upper Cervical Adjustment	Upper Cervical Adjustemnt	Upper cervical adjustemnt
Upper Cervical Adjustment	Thoracic Adjustemnt	Upper cervical adjustemnt
Thoracic Adjustment	Upper Cervical Adjustemnt	Thoracic adjustment
Thoracic Adjustment	Thoracic Adjustemnt	Thoracic adjustment

Primary Outcome Measures

Name	Time	Method
Galvanic Skin Response	Through study completion, an average of 1 week	Galvanic Skin response gives a strong measure of Sympathetic response via electrical conductivity of perspiration.
NSESSS	Through study completion, an average of 1 week	Measures PTSD symptoms in people 18 and up.
CD-RISC-25	Through study completion, an average of 1 week	Measure of adaptability
Caretaker Heart Rate Variability	Through study completion, an average of 1 week	HRV allows for an understanding of Autonomic (parasympathetic) function, via measuring the interval of R peaks in QRS complexes.
Hamilton Anxiety Rating Scale	Through study completion, an average of 1 week	Measures the severity of anxiety symptoms

Trial Locations

Locations (1)

Dr. Sid E. Williams Center for Chiropractic Research; 🇺🇸 Atlanta, Georgia, United States