Transcranial Direct Current Stimulation (tDCS) in the Primary Motor Cortex and Its Effects on Sensitivity, Pressure Pain Threshold, and Electromyographic Activity in Healthy Individuals: A Quasi-experimental Single-blind Sham-controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Pressure pain threshold through an algometer
研究概览
简要总结
The main aim of this study is to assess the short-term effects of active-tDCS (a-tDCS) on the M1 regarding sensorimotor variables such as discriminative sensation, pressure pain threshold and electromyographic activity compared with a sham-tDCS (s-tDCS) in healthy individuals. The main objective was to determine whether there were clinically relevant changes generated by tDCS and if they were superior to a sham intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •asymptomatic participants
- •men and women aged 18 to 65 years
排除标准
- •pregnancy
- •use of painkillers in the last 24 hours
- •presence of metal inside the head
- •pacemaker
- •wound on the area of electrodes' application
- •drug consumption; (j) recent application of tDCS
- •psychiatric disease impeding understanding of the study.
结局指标
主要结局
Pressure pain threshold through an algometer
时间窗: Change in pressure pain threshold immediately at the end of the intervention
Pressure pain threshold has been defined as the minimal amount of pressure at which a sense of pressure first changes to pain or discomfort
Tactile acuity threshold
时间窗: Change in tactile acuity threshold immediately at the end of the intervention
Tactile acuity threshold is an important variable to know the somatosensory state and Von Frey monofilaments and Aesthesiometer were used
Muscle recruitment through electromyographic activity
时间窗: Change in electromyographic activity immediately at the end of the intervention
The activity of surface electromyography (sEMG) during an isometric maximal voluntary contraction was measured in the biceps brachii and rectus femoris.
次要结局
未报告次要终点
研究者
Roy La Touche Arbizu
Principal Investigator
Universidad Autonoma de Madrid