NCT00590109已完成不适用
Germline BRCA1 and BRCA2 Mutations in Jewish Women Affected by Breast Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 383
- 试验地点
- 1
- 主要终点
- to further characterize inherited predisposition to breast cancer mediated by specific BRCA alleles among Jewish women.
研究概览
简要总结
The purpose of this project is to further characterize inherited predisposition to breast cancer mediated by specific BRCA alleles (BRACA1 185delAG and 5382insC; BRCA2 6174delT) among Jewish women.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patients are eligible for the study if they are over 18 years of age, identify their ancestry as Jewish (both Sephardic and Ashkenazi Jews are eligible), have or have had a diagnosis of breast cancer, and are able to give informed consent.
- •Relatives, age 18 or older, of the patients who meet eligibility criteria above and are found to have a specific BRCA1 or BRCA2 mutation if they are able to give informed consent.
排除标准
- 未提供
结局指标
主要结局
to further characterize inherited predisposition to breast cancer mediated by specific BRCA alleles among Jewish women.
时间窗: through study completion, an average of 1 year
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
撤回
不适用
Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation CarriersBRCA1 Mutation CarrierBRCA2 Mutation CarrierBreast CarcinomaNCT00899145Gynecologic Oncology Group
招募中
不适用
Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood SamplesBreast CancerOvarian CancerGynecologic CancersOvarian/Peritoneal/Fallopian CancerNCT01034033Stanford University3,300
已完成
不适用
Genetic Studies in Breast CancerBreast CancerOvarian CancerNCT00582322Memorial Sloan Kettering Cancer Center483
招募中
不适用
Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic EvaluationBRCA-Associated Breast CarcinomaNCT05763472Fondazione Policlinico Universitario Agostino Gemelli IRCCS10
Unknown
不适用
Studying Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriersbrca1 Mutation Carrierbrca2 Mutation CarrierBreast CancerNCT00897455Gynecologic Oncology Group10,000