Eeffect of Nebulized hypertonic saline solution on treatment of infant with viral bronchiolitis
- Conditions
- Acute Viral bronchiolitis.Acute bronchiolitis
- Registration Number
- IRCT138903134096N1
- Lead Sponsor
- Vice Chancellor of Research, Bushehr University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
a total of infant (2 month to 24 month of age )with mild to moderate bronchiolitis seen in aliasghar tertiary care pediatric center ED in 2008-2010(fall & winter)were randomized to double blind treatment with nebulized salbutamol in either 3% saline or 0.9% saline.
bronchiolitis: first or second episodes of respiratory distress with wheezing or sign of viral respiratory tract infections includes RR>60; 38c=T; PR>180 or coryza.
Exclusion criteria: pre-exiting cardiac or pulmonary disease; previous diagnosis of asthma or positive familial history of asthma; previous history of prematurity(GA<34w) or using ventilator at birth; severe illness that needed to immedietly hydration or decrease level of consciousness or letargia or respiratory failure & infants with RR>60; 38c=T; PR>180 second or more episodes of respiratoye distress.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in sum of RADI score and YALE clinical score. Timepoint: at first & 30 minute later. Method of measurement: physical examination.;Admission rate. Timepoint: 30 minute. Method of measurement: physical examination.
- Secondary Outcome Measures
Name Time Method Intravenous fluid use. Timepoint: 14 days. Method of measurement: physical examination.;Length of stay. Timepoint: day of discharge. Method of measurement: physical examination.;Oxygen use. Timepoint: day of discharge. Method of measurement: physical examination.;Remission of cough and wheezing. Timepoint: 1 mounth. Method of measurement: physical examination.