NCT00181116已完成4 期
Efficacy of Levetiracetam for Language Dysfunction Associated With Benign Epilepsy With Centrotemporal Spikes
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 6
- 试验地点
- 1
- 主要终点
- Language improvement
研究概览
简要总结
This study is designed to test if the language problems commonly seen in children with benign rolandic epilepsy would improve by switching anticonvulsants to levetiracetam.
详细描述
This is a 6 month study in which children on another anticonvulsant would have EEG, language testing, and a clinic visit at baseline. They would then be rapidly transitioned off of their current anticonvulsant and onto levetiracetam (Keppra). Repeat EEG and language testing would be done after 6 months to evaluate for improvement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages 6-12
- •Benign rolandic epilepsy
- •Language difficulties as reported by parents or teachers
- •On another anticonvulsant other than levetiracetam
排除标准
- •Prior use of levetiracetam
- •On 2 or more anticonvulsants
- •Language problems prior to epilepsy
- •Another seizure disorder
- •Status epilepticus within the past 6 months
- •Significant psychiatric disease
- •Progressive neurologic disease
结局指标
主要结局
Language improvement
次要结局
- Seizure control
研究者
研究点 (1)
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