A Randomized Clinical Trial Comparing the Success Rate of Pleurodesis with Thoracoscopic Talc Poudrage Combined with Indwelling Pleural Catheter versus Thoracoscopic Talc Poudrage in Patient with Malignant Pleural Effusio

Phase 3

• Conditions: Malignant pleural effusion; Thoracoscopic talc poudrage; Indwelling pleural tunnel catheter; Pleurodesis success

• Registration Number: TCTR20230312001
• Lead Sponsor: Faculty of Medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-12
• Study Completion: 2023-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

Patient with symptomatic malignant pleural effusion
Age over 18 years old
LENT score less than 5
ECOG score 0-2

Exclusion Criteria

Pregnancy
Allergy to medication and talc
Bleeding tendency
Hemodynamic instability
Recent myocardial infarction in 6 weeks
Unexpandable lung, complicated pleural effusion

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pleurodesis success rate 12 weeks percent

Secondary Outcome Measures

Name	Time	Method
Dyspnea score 1,6,12 weeks Visual analogue score ,Quality of life 12 weeks Questionnaire QoL 5D5L,Complication 1,6,12 weeks percent