A Study to Evaluate Coronary Atherosclerosis in Patients With Diabetes Mellitus
- Conditions
- Diabetes Mellitus
- Registration Number
- NCT05801432
- Lead Sponsor
- Asan Medical Center
- Brief Summary
The purpose of this study is to evaluate the natural history of coronary atherosclerosis development and progression over time by CCTA and to identify risk factors attributable to the development of coronary atherosclerosis in a Korean DM population.
- Detailed Description
Patients with diabetes mellitus, who underwent initial CCTA (coronary computed tomographic angiography) at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012, will be evaluated for inclusion in the study. All DREAM-CCTA study patients will undergo follow-up CCTA based on order from their primary physician. CCTA and demographic data, medical history, cardiovascular risk factors, and laboratory data was collected in case report forms at the time of the initial CCTA and at the time of follow-up CCTA.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 511
- Age 19 years or older
- Asymptomatic patients with type 2 DM who had undergone initial CCTA evaluation at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012
- Willing and able to provide informed written consent
- Blood test results that the Creatinine level exceeds 1.5 mg/dL
- A person with a history of anaphylaxis or allergic shock associated with a contrast medium
- Pregnant women
- Unable to undergo follow-up CCTA
- Uninterpretable CCTA
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change in coronary atherosclerosis detected by initial and follow-up CCTA about 10 years after first CCTA the natural history of coronary atherosclerotic plaque development and progression over time by CCTA
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Asan Medical Center
🇰🇷Seoul, Korea, Republic of