Assessment of force of contraction of left ventricle(chamber on left side of heart) during various stages of coronary bypass surgery(surgery for treatment of blocked heart vessels) using heart lung machine(a machine which takes over the work of heart and lungs during surgery)
Not Applicable
- Conditions
- Health Condition 1: I20-I25- Ischemic heart diseases
- Registration Number
- CTRI/2021/03/032240
- Lead Sponsor
- King George Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of ASA3 of either sex, aged between 40-70 years, scheduled to undergo on pump assisted beating heart coronary artery bypass graft surgery for isolated ischemic heart disease with triple vessel disease with ejection fraction >40%
Exclusion Criteria
1 Refusal by participant
2 Contraindication of Trans-esophageal echocardiography probe insertion
3 Right ventricular dysfunction
4 Cardiac arrhythmias or conduction defect
5 Redo cardiac surgeries
6 Pregnancy
7 Cardiomyopathies
8 Pericardial effusion
9 Regional wall motion abnormality of basal left ventricle segments
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eft ventricular ejection fraction using: <br/ ><br>1. Mitral annular plane systolic excursion <br/ ><br>2. Mitral annular tissue peak velocity of septal and lateral auunulus <br/ ><br>3.Modified Smpsons MethodTimepoint: The first two measurements will be taken at: <br/ ><br>a. after induction of anesthesia <br/ ><br>b. after sternotomy <br/ ><br>c. after pericardioctomy <br/ ><br>d. after aortic and venous cannulation <br/ ><br>e. after sternal closure. <br/ ><br> <br/ ><br>measurment of ejection fraction will be done using modified Simsons method after induction and after sternal closure
- Secondary Outcome Measures
Name Time Method 1. Heart rate <br/ ><br>2. Mean blood pressure <br/ ><br>3. Adverse effects including: <br/ ><br>a. intraoperative hypotension <br/ ><br>b. arrhythmias <br/ ><br>c.Mediastinal bleeding <br/ ><br>Timepoint: Hemodynamic variables will be observed Intraoperatively only while other variables will be also be in immediate post-operative period upto 48 hours.