A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
- Conditions
- Multiple Ground Glass Opacities (GGOs)
- Registration Number
- NCT03802981
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Brief Summary
The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study participants whose GGOs are being monitored in the active surveillance program.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 338
- Age greater than 18 years
- Have two or more GGOs on initial CT imaging
- GGOs must be measure ≤3.0 cm and ≥0.6 cm in the greatest dimension
- GGOs must be greater than half ground glass
A biopsy is not necessary for inclusion in the trial. Biopsy of a GGO, even with a diagnosis of adenocarcinoma, does not necessarily preclude enrollment in this surveillance protocol. In other words, patients with a diagnosis of adenocarcinoma are still eligible, at the discretion of the clinician and/or investigator, if they meet the above criteria.
- Patients who are actively undergoing lung cancer treatment or have a history of lung cancer, except for cases of completely resected pathologic stage IA nonsmall cell lung cancer (NSCLC). Patients with stage IA NSCLC and multiple GGOs can enroll in this active surveillance protocol after complete resection of the NSCLC and confirmation of stage on final pathologic assessment.
- The presence of any solid lesion ≥0.6 cm suspicious for malignancy.
- Patients who are actively undergoing treatment for other malignancies
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method lung cancer-specific survival 5 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (32)
Memorial Sloan Kettering Westchester
🇺🇸Harrison, New York, United States
Hartford Healthcare
🇺🇸Hartford, Connecticut, United States
Washington University School of Medicine
🇺🇸Saint Louis, Missouri, United States
Memorial Sloan Kettering Commack
🇺🇸Commack, New York, United States
George Washington University School of Medicine
🇺🇸Saint Louis, Missouri, United States
Memorial Sloan Kettering Cancer Center
🇺🇸New York, New York, United States
Roswell Park Cancer Institute (Data Collection Only)
🇺🇸Buffalo, New York, United States
Memorial Sloan Kettering Nassau
🇺🇸Uniondale, New York, United States
University of Pennsylvania (Data Collection Only)
🇺🇸Philadelphia, Pennsylvania, United States
Memorial Sloan Kettering Basking Ridge
🇺🇸Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth
🇺🇸Middletown, New Jersey, United States
Stanford University Medical Center (Data collection only)
🇺🇸Stanford, California, United States
Duke University Medical Center
🇺🇸Durham, North Carolina, United States
Lehigh Valley Health Network
🇺🇸Allentown, Pennsylvania, United States
Thomas Jefferson University Hospital
🇺🇸Philadelphia, Pennsylvania, United States
Temple University
🇺🇸Philadelphia, Pennsylvania, United States
Rush University Medical Center (Data collection only)
🇺🇸Chicago, Illinois, United States
Massachusetts General Hospital Cancer Center
🇺🇸Boston, Massachusetts, United States
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States
Allegheny Health Network
🇺🇸Pittsburgh, Pennsylvania, United States
University of Pittsburgh Medical Center
🇺🇸Pittsburgh, Pennsylvania, United States
Baylor University Medical Center
🇺🇸Houston, Texas, United States
MD Anderson Cancer Center
🇺🇸Houston, Texas, United States
University of California San Diego
🇺🇸San Diego, California, United States
McMaster University (Data Collection Only)
🇨🇦Hamilton, Ontario, Canada
University Health Network
🇨🇦Toronto, Ontario, Canada
Centre Hospitalier de l'Université de Montreal
🇨🇦Montréal, Quebec, Canada
New York Presbyterian Hospital
🇺🇸New York, New York, United States
University of Michigan
🇺🇸Ann Arbor, Michigan, United States
Memorial Sloan Kettering Bergen
🇺🇸Montvale, New Jersey, United States
Fox Chase Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
Mayo Clinic
🇺🇸Rochester, Minnesota, United States