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Clinical Trials/NCT04352270
NCT04352270
Completed
N/A

A Randomized Controlled Study of Clinic-Based Atopic Dermatitis Therapeutic Patient Education

Boston University1 site in 1 country56 target enrollmentFebruary 27, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Atopic Dermatitis
Sponsor
Boston University
Enrollment
56
Locations
1
Primary Endpoint
Change in eczema severity based on the Patient Oriented Eczema Measure (POEM)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The primary objective of this randomized trial is to determine whether comprehensive, accessible, and animation-style videos are a more effective method of therapeutic patient education (TPE) based on clinical outcomes than paper handouts in Spanish and English-speaking communities. The clinical outcomes being measured are the severity, sleep affected by atopic dermatitis (AD), and the amount of itch experienced.

Detailed Description

Patients will be recruited, stratified, and then randomly assigned into one of two intervention groups.The patient participants will be children anywhere on the spectrum of mild to severe AD and they will be stratified into four strata: a) Those with severe AD and no medical intervention escalation, b) Those with mild AD and no medical intervention escalation, c) Those with severe AD and medical intervention escalation, and d) Those with mild AD and medical intervention escalation. Group 1 will be a paper handout for group 1 and an educational video for group 2 as a form of TPE. Subjects will be recruited in clinic after they are screened for AD during their regular dermatology appointment. The research team will provide the patient and parent with a brief introduction to the study, what it involves for the patient, any foreseeable risks, and the compensation. If they agree to participate, a consent/permission form will be given to the parent/guardian to sign. After an initial evaluation of the patient's AD, subjects will receive an initial survey and POEM questionnaire on an iPad via RedCap that will address the condition of their AD. The patient will be administered a form of TPE as the intervention. The intervention will first be viewed/read in clinic, followed by a brief set of questions from the research team to determine the amount of information retained on an immediate level. A follow-up appointment will be scheduled for the patient. Group 2 will receive a slip of paper with a link to the videos, so the TPE will be accessible outside the clinic.

Registry
clinicaltrials.gov
Start Date
February 27, 2023
End Date
September 21, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Boston Medical Center (BMC) patients under the age of 18 diagnosed with AD and their parents/legal guardian
  • Spanish or English speakers
  • Have access to the internet

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change in eczema severity based on the Patient Oriented Eczema Measure (POEM)

Time Frame: baseline, up to 2 months

The Patient Oriented Eczema Measure (POEM) is a validated 7 item instrument with response categories from 0 to 4 where No days = 0, 1-2 days = 1, 3-4 days = 2, 5-6 days = 3, Every day = 4. Scoring for the POEM ranges form 0 to 28 and is interpreted by 0 to 2 = Clear or almost clear, 3 to 7 = Mild eczema, 8 to 16 = Moderate eczema, 17 to 24 = Severe eczema, 25 to 28 = Very severe eczema.

Change in eczema severity based on the Eczema Area and Severity Index (EASI)

Time Frame: baseline, up to 2 months

The Eczema Area and Severity Index (EASI) is an investigator-assessed instrument measuring the severity of clinical signs in atopic dermatitis (AD). The suggested severity strata for the EASI are: 0 = clear; 0·1-1·0 = almost clear; 1·1-7·0 = mild; 7·1-21·0 = moderate; 21·1-50·0 = severe; 50·1-72·0 = very severe

Change in the severity of itch

Time Frame: baseline, up to 2 months

An investigator developed survey completed by participants with questions about itch will be used to collect data to assess this outcome.

Change in sleep quality

Time Frame: baseline, up to 2 months

An investigator developed survey completed by participants with questions about sleep quality will be used to collect data to assess this outcome.

Secondary Outcomes

  • Change in patient/parent confidence(baseline, up to 2 months)
  • Change in knowledge of coping with Atopic Dermatitis (AD)(baseline, up to 2 months)
  • Change in the overall quality of life(baseline, up to 2 months)
  • Satisfaction with therapeutic patient education (TPE)(up to 2 months)
  • Atopic Dermatitis related costs(6 months)

Study Sites (1)

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