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Establishment of Retrospective and Prospective Multicenter Cohort for Chronic Hepatitis B

Not Applicable
Active, not recruiting
Conditions
Certain infectious and parasitic diseases
Registration Number
KCT0001297
Lead Sponsor
Yonsei University Health System, Severance Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Active, not recruiting
Sex
All
Target Recruitment
500
Inclusion Criteria

Inclusion criteria
1. Subject aged 20 years or older
2. Subject who has been diagnosed with chronic hepatitis B (HBs Ag (+) for minimum of 6 months)
3. Subject who is currently under clinical follow-up at the registered institution
4. Subject who has previously undergone or who can undergo liver fibroscan at the time of registration
5. Subject who has given informed consent to the enrollment

Exclusion Criteria

Exclusion criteria
1. Subject with decompensated liver cirrhosis or hepatocellular carcinoma at the time of initial liver fibroscan
2. Subject who had previously undergone antiviral therapy for chronic hepatitis B
3. Subject who are concomittantly infected with HCV, HDV or HIV
4. Subject with chronic alcoholism defined as equal to or greater than 40g of alcohol for duration of 5 years or longer
5. Subject who has been diagnosed with right sided heart failure
6. Subjects whose liver fibroscan result is not valid
7. Subject who is considered ineligble by the researcher
8. Subject who is pregnant at the time of registration

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Development of liver-related events
Secondary Outcome Measures
NameTimeMethod
Hepatocellular carcinoma
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