A Clinical Study of Hyperthyroidism in Children
Recruiting
- Conditions
- Hyperthyroidism
- Registration Number
- NCT06570967
- Lead Sponsor
- Shengjing Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion Criteria:<br><br> 1. Age =14 years old<br><br> 2. Initial diagnosis of hyperthyroidism<br><br>Exclusion Criteria:<br><br> 1. Hyperthyroidism had been treated with medication in other hospitals,<br><br> 2. History of autoimmune hepatitis, viral hepatitis, hematological diseases, bone<br> marrow or liver transplantation,<br><br> 3. Patients with incomplete clinical data
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Observational [Patient Registry]
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Remission of hyperthyroidism in children treated with methimazole. Remission is defined as having clinical and biochemical euthyroidism(FT3, FT4 and TSH are normal) without methimazole treatment for at least 12 months.;Adverse effects of methimazole in the treatment of hyperthyroidism in children. Adverse effects are defined as having neutropenia (absolute neutrophil count< 1500/µL), liver dysfunction (AST or ALT> 60 IU/L), rash, arthralgia, myalgia, et al.
- Secondary Outcome Measures
Name Time Method Relapse of hyperthyroidism in children treated with methimazole. Relapse was defined as having clinical and biochemical hyperthyroidism (FT3 and FT4 increased and TSH decreased) after discontinuation of methimazole.