ITMCTR2000002994尚未招募4 期
Evidence-Based Optimization and Therapeutic Mechanism of Traditional Chinese Medicine in Prevention and Treatment of Coronary Heart Disease (Angina Pectoris-Myocardial Infarction-Heart Failure)
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 18 至 —（—）
- 性别
- All
入选标准
- •1. Clearly diagnose patients admitted to acute heart failure;
- •2. Aged >= 18 years;
- •3. Voluntarily participate in and sign the informed consent form;
- •4. Randomization can be assigned within 16 hours of admission (including outpatient, ward, ICU/CCU or emergency department).
排除标准
- •1. The duration of systolic blood pressure during the screening period was less than 90mmHg.
- •2. It is known that hypertension patients refuse treatment, or systolic blood pressure >= 180mmHg, diastolic blood pressure >= 110mmHg after drug treatment;
- •3. Before entering the group, the hematocrit is less than 25%, the hemoglobin (Hgb) is less than 8.0g / dl, or there is a history of blood transfusion within 14 days before screening, or gastrointestinal bleeding that is life-threatening actively;
- •4. Body temperature > 38 degree C (oral or equivalent) or sepsis or active infection requiring intravenous antimicrobial therapy;
- •5. Within 60 days before entering the group, major neurological events occurred, including cerebrovascular events.
- •6. Known liver injury or potentially severe liver disease (abnormal liver function) (ALT or AST > 3 times normal, alkaline phosphatase or bilirubin > 2 times normal);
- •7. Patients with known severe impairment of renal function (eGFR < 25mL/min/1.73m2), or acute contrast nephropathy planned or being dialyzed or screened;
- •8. At present or within 30 days before entering the group, there is clinical evidence of acute coronary syndrome. (note: the diagnosis of acute coronary syndrome is a clinical diagnosis, considering that troponin concentration may significantly increase in acute heart failure, only the increase of troponin concentration is not enough to diagnose acute coronary syndrome.).
- •9. Acute heart failure caused by known severe arrhythmias (including any of the following: ventricular tachycardia, bradycardia with ventricular rate < 45 beats / min, or atrial fibrillation / flutter with ventricular rate > 120 beats / min);
- •10. It is known to have acute myocarditis, hypertrophic obstructive, invasive or contractile cardiomyopathy (excluding the restricted mitral filling pattern shown by Doppler echocardiography), complex congenital heart disease, constrictive pericarditis or tamponade, etc. (obvious left ventricular outflow tract obstruction, such as obstructive hypertrophic cardiomyopathy or severe aortic stenosis, or aortic valve area < 1.0 cm2 or previous or current echocardiography showed mean pressure difference > 50mmhg), or severe mitral stenosis;
- •11. Severe aortic insufficiency or severe mitral regurgitation require surgery or percutaneous interventional therapy.
- •12. Dyspnea caused by non-cardiac causes, such as acute or chronic respiratory diseases or infections (i.e. severe chronic obstructive pulmonary disease, pulmonary embolism, bronchitis, pneumonia);
- •13. A patient who has received any organ transplant or is currently receiving an organ transplant (that is, patients who are not excluded from the waiting list for transplant);
- •14. Currently (including within 2 hours before screening) or planned to provide mechanical circulation support (endotracheal intubation mechanical ventilation; intra-aortic balloon pump or any ventricular assist device; hemofiltration or dialysis);
- •15. Used trial drugs 3 months before screening or trial, or participated in other clinical researchers within 30 days before treatment;
- •16. Unable to follow the doctor's advice or complete the follow-up treatment or follow-up process;
- •17. Pregnant or lactating women or those who are prepared to give birth within 3 months after the cessation of medication (women with reproductive potential, that is, all women who are physically able to conceive, unless they use effective contraceptive methods during the study and
研究者
相似试验
招募中
不适用
Clinical study on evidence-based optimization scheme of ICU delirium treatment with traditional Chinese medicineIntensive Care DeliriumITMCTR1900002776Affiliated Hospital of Chengdu University of traditional Chinese Medicine
招募中
不适用
Evidence-Based Evaluation and Effect Mechanism of Traditional Chinese Medicine on the Prevention and Treatment of Sepsis Based on Truncated Torsion StrategysepsisITMCTR2100004722ongHua Hospital Shanghai University of Traditional Chinese Medicine
进行中（未招募）
1 期
OPTIMISE: A study investigating if analysis of cancer DNA in blood can be used to guide adjuvant treatment in patients with advanced colorectal cancerMedDRA version: 21.0Level: PTClassification code 10010035Term: Colorectal cancer stage IVSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)MedDRA version: 21.0Level: PTClassification code 10052358Term: Colorectal cancer metastaticSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2020-004524-41-DKAarhus University Hospital/Karen-Lise Garm Spindler350
招募中
不适用
Study on evidence-based evaluation and therapeutic mechanism of integrated Chinese and Western medicine for treatment of diabetic foot -- An evidence-based evaluation of The combination of Rubber Shengji Paste and compound bromelain to promote the healing of the exposed wound of diabetic foot tendoDiabetic footITMCTR2100004318The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
尚未招募
1 期
The efficacy and safety of chinese herbal medicine Shen-Qi Hua-Yu formula in patients with diabetic lower extremity artery disease: a multi-centre, randomized, double-blind, placebo-controlled trialDiabetic Lower Extremity Artery DiseaseITMCTR1900002645Hospital of Chengdu University of Traditional Chinese Medicine