An Open-label Single-arm Prospective Study of Continuous Intervention with Designated Treatment Application for NASH (Non-Alcoholic Steatohepatitis) Patients
- Conditions
- non-alcoholic steatohepatitis
- Registration Number
- JPRN-UMIN000029835
- Lead Sponsor
- The University of Tokyo Hospital
- Brief Summary
After the 48-week DTx intervention, improvement of the NAS was observed in 68.4% (13/19) of patients. The mean change in the NAS from the baseline to the end of the intervention was -2.05 (p = 0.007 as compared with the threshold of -0.7).A decrease of the NAS by mora than 2 points was achieved in 11 (57.9%). The average weight loss at the end of the intervention was 8.3% (p < 0.001). Reduction of the fibrosis stage was observed in 58.3% when the analysis was limited to patients with stage F2/3 fibrosis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Not provided
1.patients do not agree 2.patients who are regarded as difficult to use a smartphone 3.patients with viral hepatitis 4.patients diagnosed as autoimmune hepatitis 5.patients diagnosed as metabolic disease 6.patients who are histologically diagnosed as cirrhosis 7.patients with current or history of hepatocellular carcinoma 8.patients with condition that cannot be performed liver biopsy safely
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method