Oral Paracetamol as Preemptive Analgesia for Labor Pain
- Registration Number
- NCT01817829
- Lead Sponsor
- Ain Shams University
- Brief Summary
It is a double blinded randomized control trial assessing the use of Oral paracetamol in managing the intrapartum pain.
- Detailed Description
It is a double blinded randomized control trial comparing the use of Oral paracetamol to placebo in managing the intrapartum pain.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- primigravida
- The gestational age between 37- 42 weeks
- Not seeking analgesia
- Singleton pregnancy
- vertex
- Spontaneous onset of labour
- 1st stage of labour (less than 5 cm)
Exclusion Criteria
- Extreme of age (below18-above 40)
- Multiparous
- Multiple gestation
- Malpresentation
- Congenital or acquired pelvic abnormalities(eg. Poliomyelitis)
- Any medical disorder with pregnancy
- Induction of labour
- Advanced 1st stage > 5 cm
- Use of any other kind of analgesia before recruitment in the study
- Scared uterus
- Fetal distress
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description placebo placebo placebo 2 tablets containing Starch PO paracetamol paracetamol paracetamol 2 tablets1000mg PO.
- Primary Outcome Measures
Name Time Method Efficacy intrapartum To document the efficacy of oral paracetamol, in pregnant women in labor, as demonstrated by the degree of pain relief and need for additional analgesia during the labor process and the early postpartum period.
- Secondary Outcome Measures
Name Time Method Safety Start of medication till 24 hours postpartum To document safety and evaluate adverse events recorded during the study either maternal or fetal.
Duration of labor Start of medication till delivery of fetus. To assess the effect of the duration of labor.