Postprandial VLDL-TG Metabolism
Completed
- Conditions
- Type 2 Diabetes
- Registration Number
- NCT01961024
- Lead Sponsor
- University of Aarhus
- Brief Summary
In thise study, we aim to determine the effect of meal fat on VLDL-TG kinetics in type 2 diabetic and healthy subjects matched for BMI in order to elucidate the potential pathophysiological differences in VLDL-TG FA channeling towards oxidation and storage in abdominal and leg subcutaneous adipose tissue. Specifically, we want to measure, by way of fat and muscle biopsies, the quantitative postprandial storage of VLDL-TG FA's in skeletal muscle and adipose tissue in relation to a series of tissue specific proteins and enzymes that might be involved in regulating skeletal muscle and adipose tissue FA storage.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 21
Inclusion Criteria
- Written consent
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Exclusion Criteria
- Known diseases
- Alcohol abuse
- Smoker
- Regular use of medicine
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VLDL-TG storage in adipose tissue 3 hours
- Secondary Outcome Measures
Name Time Method 18F-THA fractional storage 6 Hours
Trial Locations
- Locations (1)
Department of Endocrinology MEA, Aarhus Hospital
🇩🇰Aarhus C, Please Select, Denmark