Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion

Mayo Clinic1 site in 1 country52 target enrollmentFebruary 21, 2019

Overview

Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.

All subjects will complete pre and post procedure assessments prior to undergoing a planned surgery/anesthetic standard of care.

Registry

clinicaltrials.gov

Start Date

February 21, 2019

End Date

April 10, 2025

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Sponsor

Responsible Party

Principal Investigator

Arnoley (Arney) S. Abcejo

Principal Investigator

Mayo Clinic

•Male or Female \>16 years of age with a recent concussion (\<10 weeks) from planned procedure under anesthesia.

•Neurologic history including history of severe cognitive disease, disorder, or delay, attention disorder, moderate to severe TBI history, neurovascular order or trauma.

Wide Range Achievement Test Fourth Edition, WRAT-4

Time Frame: Pre-anesthetic to one week Post-anesthetic

Change in WRAT-4

Sport Concussion Assessment Tool - 5th edition, SCAT-5(Pre-anesthetic to one week Post-anesthetic)
Oral morphine equivalent of consumed opioids(Post-operatively to hospital discharge, up to 10 days.)
Length of hospital stay(Post-operatively to hospital discharge, up to 30 days.)
Cognitive Deficits identified by NeuroPsychometric Cognitive Testing(Pre-anesthetic to one week Post-anesthetic)
Numeric Pain Scale 0-10(Post-operatively to hospital discharge, up to 10 days.)