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Effect of dexmedetomidine on blood loss and patient outcomes in orthognathic surgery

Phase 4
Completed
Conditions
orthognathic surgery patients
dexmedetomidine, blood loss, orthognathic surgery
Registration Number
TCTR20230818002
Lead Sponsor
self support
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
60
Inclusion Criteria

1. patient undergoing bimaxillary orthognathic surgery
2. ASA classification 1 or 2

Exclusion Criteria

1. patient with coagulopathy
2. patient with bradycardia, cardiac dysrhythmias
3. known allergy to the study drugs
4. pregnancy and lactation.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
blood loss, postoperative hemoglobin, blood transfusion the end of the operation intra-operative estimated blood loss, postoperative hemoglobin, incidence of blood transfusion
Secondary Outcome Measures
NameTimeMethod
vital signs the end of operation Intra-operative heart rate, mean arterial pressure, and the amount of vasopressure usage,pain score, opioids requirement 24 hours after operation overall pain score, amount of opioid drug usage(intraoperative, postoperative in recovery room and in first 24 hr),operative time, quality of operative visual field, surgeons' satisfaction the end of operation operative time in minutes, Fromme's scale, Likert scale ,hospital stays, side effects the end of operation and 24 hours after operation episode of bradycardia, hypotension, arrhythmia and nausea/vomiting
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