Efficacy of Dexmedetomidine infusion on the bleeding in endoscopic sinus surgery.
Phase 2
- Conditions
- Chronic sinusitis.Chronic sinusitis
- Registration Number
- IRCT201606211138N23
- Lead Sponsor
- Guilan University of Medical Science, Vice Chancellor for Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Patients aged between 16-60 years who undergo endoscopic sinus surgery; those with hemoglobin more than 10 mg/dL; normal clotting time and bleeding time; normal PT; PTT; INR; no history of airways problems and systemic disease or Mental disorders; no history of the anesthetic drugs sensitivity or any other medication and no history of bleeding disorders (such as hemophilia) ;Exclusion criteria: Use of anticoagulants such as heparin 48 hours before surgery; history of acute and chronic renal failure; diabetes; stroke; coronary artery disease; hypertension; deep vein thrombosis; pulmonary embolism; peripheral vascular diseases; pregnancy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of bleeding during surgery. Timepoint: in time intervals between 15; 30; 60 and 90 minutes. Method of measurement: scale Boezaart.
- Secondary Outcome Measures
Name Time Method Systolic and diastolic blood pressure and Mean Arterial Pressure. Timepoint: in time intervals between 15; 30; 60 and 90 minutes. Method of measurement: Mercury manometers.;Heart rate. Timepoint: in time intervals between 15; 30; 60 and 90 minutes. Method of measurement: Electrocardiogram.;Surgeon satisfaction. Timepoint: in time intervals between 15; 30; 60 and 90 minutes. Method of measurement: Likert scale.;Duration of surgery. Timepoint: in time intervals between 15; 30; 60 and 90 minutes. Method of measurement: clock.