TO UNDERSTAND THE EFFECTIVENESS OF HINGUVADI GHRITAPANA AND JATAMAMSADI TAILA NASYA IN THE TREATMENT OF AUTISM IN CHILDREN

Not yet recruiting

Conditions: Autistic disorder. Ayurveda Condition: Autism ,

Registration Number: CTRI/2021/12/038875

Lead Sponsor: Shri BMK Ayurveda Mahavidyalaya

Brief Summary: Autism is a heterogeneous neurodevelopmentalcondition manifesting in early childhoo The abilities and needs of people with autismvary. While some can live independently , most of them will have severedisabilities and require lifelong care and support .According to WHO, it is anemerging global concern with 1 in 160 children diagnosed with autism. In India ,1 in every 88 children is diagnosed with Autism. Itis approximately four times more common in males than females.

Atpresent,no medications are established to treat its core symptoms. Risperidone and Aripiprazole arethe only FDA approved medications currently used, targetingthe irritability seen with this diagnosis. Moreover, Children and adolescentswith autism appear to be more susceptible to adverse effects with thesemedications.The line of treatment, commonly used are speechtherapy, psychotherapy, occupational therapy, behaviour training and dietarymodification. These treatments are time and staff intensive.Becauseof all the above reasons, there is a need to find a new approach and modalityfor Autism . In Autism ,thebrain and components of the brain are affected .Available evidencesuggests that around 21-70% of children with autism have gastrointestinal symptoms. This attributes to theconcept of gut brain axis.

In *Ayurveda,* the exact correlation is not yet clearly identified.Autism can be understood under the concept of *Unmada*.A defective digestive and metabolicfunction is postulated as the root cause of *Unmada*

In this study, the drugs are takenfrom the *Aparajitha* yoga mentioned for*Sarva manoroga*, by *Acharya Sushrutha* [8].By virtue of the mode of action of *Nasya* , we can expect apositive effect on the brain. With this hypothesis, we are administering the *Jatamamsadi Taila Nasya* in this study.Inthis study we are administering *Hinguvadi ghrita* orally to address the gastrointestinal symptoms

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 20

Inclusion Criteria

Children satisfying diagnostic criteria.

Exclusion Criteria

At the time of enrollment, If the child is found to be non inclusive due to underlying health condition or medication will be excluded Children with any acute or chronic, Local or systemic infection will be excluded Children with any congenital malformations Children who are currently under any other medication will be excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
There will be significant effect of Hinguvadi Ghritapana and Jatamamsadi Taila Nasya in the management of autism	7TH,22ND AND 45TH DAYS

Secondary Outcome Measures

Name	Time	Method
There will be significant effect of Hinguvadi Ghritapana and Jatamamsadi Taila Nasya in the management of autism	7TH,22ND AND 45TH DAYS

Trial Locations

Locations (1): KLE Ayurveda Hospital
🇮🇳
Belgaum, KARNATAKA, India
KLE Ayurveda Hospital
🇮🇳Belgaum, KARNATAKA, India
Dr Vaishnavi V
Principal investigator
9790355971
vaishnaviv.vijayan@gmail.com