Effect of High Flow Tracheostomy Device for weaning from Mechanical Ventilatio

Phase 4

Completed

• Conditions: Mechanical Ventilation; Tracheostomy; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12616001145493
• Lead Sponsor: The Prince Charles Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Written informed consent
Male or female over 18 years of age
Tracheostomy in situ
Mechanical ventilation time over 96hrs

Exclusion Criteria

Patient refusal
Patients unable to tolerate low flow oxygen as deemed by treating doctor
Pneumothorax

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in tracheal airway pressure as measured by a 6Fr cannula placed in the tracheostomy tube connected to a pressure transducer<br><br><br>[At 15 minutes of standard treatment a 2 minute continuous reading will be undertaken. A further 2 minutes of continuous data will be collected at the end of 15 minutes of high flow therapy. A 15 minute washout period of standard treatment ( low flow) will be conducted between interventions];Changes in EELV as measure by EELI using EIT[At 15 minutes of standard treatment a 2 minute continuous reading will be undertaken. A further 2 minutes of continuous data will be collected at the end of 15 minutes of high flow therapy. A 15 minute washout period of standard treatment ( low flow) will be conducted between interventions]

Secondary Outcome Measures

Name	Time	Method
Changes in oxygenation as measured on arterial blood gas (ABG)[At 15 minutes of standard treatment an ABG will be taken. A further ABG will be collected at the end of 15 minutes of high flow therapy. A 15 minute washout period of standard treatment ( low flow) will be conducted between interventions];Changes in subjective dyspnoea score (modified Borg score)[At 15 minutes of standard treatment a modified Borg score will be undertaken. A further modified Borg score will be collected at the end of 15 minutes of high flow therapy. A 15 minute washout period of standard treatment ( low flow) will be conducted between interventions];Changes in respiratory rate as determined by EIT<br><br><br>[At 15 minutes of standard treatment a 2 minute continuous reading will be undertaken. A further 2 minutes of continuous data will be collected at the end of 15 minutes of high flow therapy. A 15 minute washout period of standard treatment ( low flow) will be conducted between interventions]