Testing of Radiofrequency Coil for Clinical 19F MRI

Not Applicable

Completed

• Conditions: Diagnostic Imaging
• Interventions: Device: MRI

• Registration Number: NCT02687750
• Lead Sponsor: Western University, Canada

Brief Summary

Testing of a dual tuned proton/fluorine MRI radio frequency coil

Images were collected from plastic fluorine phantoms taped to the upper thigh of health volunteers.

This trial was performed as part of an application for a Health Canada Investigational Device Exemption (Protocol # 226949)

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2016-02
• Study First Submitted: 2016-02-02
• Study First Submitted QC: 2016-02-16
• Last Update Submitted: 2016-02-16
• Study First Posted: 2016-02-22
• Last Update Posted: 2016-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

• Healthy Volunteer

Exclusion Criteria

• MRI incompatible patient
• claustrophobia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
MRI	MRI	Eppendorf tubes containing 10% fluorine-19 diluted in agar were taped to the upper thigh of participants. Investigational device was used to image the phantom with Magnetic resonance imaging (MRI). Imaging was performed for anatomical (proton) and fluorine (agent detection). Total scan time was under 1 hour. Objectives: * Verify RF coil functionality * Obtain preliminary detection threshold limits using a human coil loading

Primary Outcome Measures

Name	Time	Method
Measure signal repeatability in different patients	1 hour of scanning	MRI signal strength is expected to vary slightly based on patient weight.
Verify radio frequency coil imaging functionality on humans	1 hour of scanning	Proof of successful MRI signal acquisition with use of investigation device.