Effect of ARB on ambulatory blood pressure and cardiovascular remodeling in hypertensives on hemodialysis
Phase 4
- Conditions
- Hypertension, end-stage renal failure on hemodialysis
- Registration Number
- JPRN-UMIN000000659
- Lead Sponsor
- Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
Malignancy, acute myocardial infarction/unstable angina, collagen diseases, acute renal failure, severe liver disorder, history of hypersensitivity to the administered ARB, pregnant women, or women suspected of being pregnant
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Ambulatory BP monitering (mean BP, BP and HR variability) 2) UCG, carotid echogram (IVSd, LVDd, LVPWd, LVDs, FS, EF, E/A, DcT, LAD, IMT) 3) ABI/baPWV 4) Blood chemistry Endocrine: catecholamine, ANP, BNP, PRA, PAC Coagulation: fibrinogen Glucose: blood glucose, IRI Serological: CRP Oxidative stress: adiponectin, MDA-LDL, AGE
- Secondary Outcome Measures
Name Time Method