Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Asana Adjustment
- Sponsor
- Zhuan Zhang
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Changes in the level of Cardiac output
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
The prone position is a special position often used for spinal surgery. As a special position of general anesthesia, after induction of general anesthesia, severe hemodynamic fluctuations often occur when the supine position is changed to the prone position, which seriously affects the patient's circulatory and respiratory functions.
Investigators
Zhuan Zhang
Principal Investigator
Yangzhou University
Eligibility Criteria
Inclusion Criteria
- •Prone spine surgery after general anesthesia is planned.
- •Age 18\~85 years old.
- •ASA grade I or II.
- •BMI18.3-30kg/m2
Exclusion Criteria
- •Unstable angina or myocardial infarction, coronary heart disease, congestive heart failure, structural heart disease, arrhythmia within 6 months;
- •Increased intracranial pressure and central nervous system injury or disease;
- •Severe hypertension
- •Patients with other diseases affecting their own circulatory system.
- •Have or have a history of severe mental disorders;
- •Bleeding volume \>600ml or intraoperative blood transfusion treatment.
- •Severe liver and kidney insufficiency
Outcomes
Primary Outcomes
Changes in the level of Cardiac output
Time Frame: Preoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone position
Cardiac output
Change in Blood pressure
Time Frame: Preoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone position
Hemodynamics
Secondary Outcomes
- Intra-abdominal pressure level(Preoperatively,5 minute after anesthesia induction,Immediately before the prone position, Immediately after the prone position,1 minute after prone position, 3 minute after prone position,10 minute after prone position,Half an hour after prone position)
- Vasoactive drugs(Intraoperatively)