Comparision of effect of adavanced and leukocyte platelet rich Fibrin on healing of extraction socket of single rooted teeth

Not yet recruiting

• Conditions: Dental caries, unspecified, ,

• Registration Number: CTRI/2022/10/046471
• Lead Sponsor: Dr Rutuja Deshmukh

Brief Summary

The study will comprise of 20 patients visiting to the Department of Oral and Maxillofacial Surgery, requiring bilateral extraction of single rooted teeth, as per inclusion criteria. Sides will be assigned randomly for placement of A-PRF and L-PRF and operator blinding will be done.

 Radiologic examination of each patient will be performed and all will be treated by the same surgeon and assistant. Extraction will be performed using nerve blocking agents -lignocaine with adrenaline (1:2,00,000) locally by giving required blocks for extraction. The tooth will be loosened with elevator and extracted by using suitable forceps. After removal of the tooth, the A�’PRF or L�’PRF will be placed into the socket. In all cases, a sterile physiological saline solution containing no antibacterial agent will be used to clean the socket left from the extraction; then, A�’PRF or L�’PRF will be placed inside the tooth socket followed by closing the wound with 3�’0 silk suture. A gauze pad will be placed in the surgical area and the patient will be asked to bite on for 30 min. Stitches will be removed after 7 days.

Post-surgical care: Patient will be placed on antibiotics and analgesics. Clinical parameters will be evaluated after 1 day,3days,7days and 3 and 6 months

.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-19
• Last Update Posted: 2023-06-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• 1)Patient requiring bilateral extraction of single rooted teeth.
• 2)Patient’s age: 15-40 3)Systemically healthy patients 4)Co-operative, motivated and hygiene conscious patients.

Exclusion Criteria

• 1)Patients with history of systemic diseases, allergies or drug usage.
• 2. Individual had a prior use of non-steroidal anti-inflammatory drugs or antimicrobial drugs in the last 3 months.
• 3. Pregnant or lactating women.
• 4. Patient who has undergone periodontal treatment in last 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
healing of extraction socket	1 day,3days,7days and 3 and 6 months

Secondary Outcome Measures

Name	Time	Method
bone density	3 and 6 months

Trial Locations

Locations (1)

VSPM dental college and research centre Nagpur; 🇮🇳 Nagpur, MAHARASHTRA, India

VSPM dental college and research centre Nagpur

🇮🇳Nagpur, MAHARASHTRA, India

Dr Rutuja Deshmukh

Principal investigator

8329353714

rutuja.deshmukh1908@gmail.com