The effect of bronchodilators on lung ventilation in chronic obstructive pulmonary disease

Phase 4

Completed

• Conditions: Chronic Obstructive Pulmonary Disease; Respiratory - Chronic obstructive pulmonary disease

• Registration Number: ACTRN12607000482460
• Lead Sponsor: The Woolcock Institute of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-09-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Subjects must have a doctor diagnosis of COPD, greater than 15pack year smoking history and obstructed lung function that cannot be normalised with bronchodilator. Subjects must all be over the age of 50 with no history of asthma or allergic disease.
Minimum age: 50 years for females and 40 years for males

Exclusion Criteria

Females under the age of 50years

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary Outcome 1: Ventilation perfusion before and after treatment[Timepoint: One hour after drug administration]

Secondary Outcome Measures

Name	Time	Method
Secondary Outcome 1: Ventilation heterogeneity measured using multiple breath nitrogen washout technique[Timepoint: One hour after drug administration]