Dietary Factors and Risk of Gallbladder Carcinoma in China
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- the The demographic, reproductive, and lifestyle characteristics
研究概览
简要总结
The purpose of this study is to see how people's diets, other aspects of their lifestyles affect their chances of getting gallbladder carcinoma in China. This survey will enroll 100 patients who have had gallbladder carcinoma，as well as controls with gallstones. The investigators will compare these two groups of subjects to see what factors may lead to gallbladder carcinoma.
详细描述
The investigators will conduct a case-control study in 10 hospitals from China. Cases will be the patients with newly-diagnosed gallbladder carcinoma. The controls will be matched （1：1）by sex，race and age which will be selected from the patients receiving cholecystectomy due to gallstones from the same hospital with the cases.
There will be 100 cases with gallbladder carcinoma, 100 controls. The investigators will interview participants about known and potential risk factors for gallbladder carcinoma and obtain information on diet. The investigators will obtain the blood and urine samples for further analysis of metabolomics studies. The investigators will use logistic regression to determine odds ratios for disease with various exposures.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosed with gallbladder carcinoma by imaging tests (cases) Diagnosed with chronic cholecystitis by imaging tests (hospital controls)
排除标准
- •The pathology diagnosis and imaging does not matched Patients with other malignant tumors Patients with other severe systemic diseases
结局指标
主要结局
the The demographic, reproductive, and lifestyle characteristics
时间窗: 2017-2019
Cases and controls were interviewed by one of three research assistants with a standard questionnaire to elicit information about demographic, reproductive, and lifestyle characteristics.
次要结局
未报告次要终点
研究者
Yingbin Liu, MD, PhD, FACS
vice-president，Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
Shanghai Jiao Tong University School of Medicine