Tattoo Particles: Picosecond Laser Versus Nanosecond Laser

Recruiting

• Conditions: Tattoo; Pigmentation
• Interventions: Other: nanosecond laser treatment + measurement with a multiphoton tomography system; Other: picosecond laser treatment + measurement with a multiphoton tomography system

• Registration Number: NCT06431464
• Lead Sponsor: Universitätsklinikum Hamburg-Eppendorf

Brief Summary

- For treating unwanted tattoos, the gold standard treatment is a nanosecond or picosecond laser. However, comparative microscopic analysis is limited. Therefore, the aim of the present study is to analysis morphological changes of tattoo particles and surrounding tissue in human skin.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-01
• Study First Submitted: 2024-02-19
• Status Verified: 2024-05
• Study First Submitted QC: 2024-05-27
• Last Update Submitted: 2024-05-27
• Study First Posted: 2024-05-28
• Last Update Posted: 2024-05-28
• Primary Completion: 2024-06-30
• Study Completion: 2024-07-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• healthy patients who plan a laser treatment of their unwanted tattoo/ tattoos at our department

Read More

Exclusion Criteria

• laser pretreatment of their tattoos to be treated
• pregnancy, breast feeding
• open wound on the area to be treated

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Nanosecond laser	nanosecond laser treatment + measurement with a multiphoton tomography system	Patients with unwanted tattoos who plan a nanosecond laser treatment will be recruited for measurements using a multiphoton-tomography system.
Picosecond laser	picosecond laser treatment + measurement with a multiphoton tomography system	Patients with unwanted tattoos who plan a picosecond laser treatment will be recruited for measurements using a multiphoton-tomography system.

Primary Outcome Measures

Name	Time	Method
Distribution of tattoo particles	6 weeks and 12 weeks post-treatment	Distribution though the epidermal and dermal layers after picosecond or nanosecond laser treatment.
Size of intercellular spaces	6 weeks and 12 weeks post-treatment	Size of intercellular spaces after picosecond or nanosecond laser treatment.
Size of keratinocytes	6 weeks and 12 weeks post-treatment	Size of keratinocytes after picosecond or nanosecond laser treatment.
Size of tattoo particles	6 weeks and 12 weeks post-treatment	Size of tattoo particles after picosecond or nanosecond laser treatment.

Trial Locations

Locations (1)

University Medical Center Hamburg-Eppendorf; 🇩🇪 Hamburg, Germany