Vitamin B1-6-12 and vitamin B12 to improve the reduced sensation from Bilateral Sagittal Split Ramus Osteotomy: a prospective randomised double blind controlled clinical trial
- Conditions
- nerve injuryrecovery of neurosensory disturbance after Bilateral Sagittal Split Ramus Osteotomy.vitamin Borthognathic surgeryneurosensory disturbance
- Registration Number
- TCTR20181030001
- Lead Sponsor
- Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
1.BSSRO procedure with or without maxillary procedure (without genioplasty) and have reduced sensation after surgery (GSS≤12)
2.Aged between 20-50 years
3.Healthy patient, no medical problems
4.No numbness or unusual feeling on the face before surgery
5.No psychological problems
6.No infection problems
7.No sensitivity to vitamin B
1.Perioperative complications such as bone exposed, partial or complete nerve dissection, excessive bleeding or unfavorable bone fracture
2.Postoperative complications such as postoperative infection, the operation that need second operation (for example: broken bur)
3.Patient with postoperative dysesthesia that need microneurosurgery
4.Patient who receive other medication that influence nerve healing
5.Patient lost follow-up in 6 months after surgery
6.Non co-operative patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The recovery of neurosensory disturbance immediately, 1 week, 1 month, 3 months and 6 months after BSSRO Clinical Neurosensory Test with static and moving 2 point discrimination, light touch and pinprick
- Secondary Outcome Measures
Name Time Method Quality of life of patients immediately, 1 week, 1 months, 3 months and 6 months after BSSRO Questionaire