â??Comparison of single and multidose pharmacokinetics of Posaconazole eye dropsâ??
Phase 3
- Conditions
- Health Condition 1: H251- Age-related nuclear cataract
- Registration Number
- CTRI/2023/07/055226
- Lead Sponsor
- Prof M Vanathi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients and healthy volunteers consent to participate in this study
Exclusion Criteria
patients less than 18 years of age
not willing to participate in this study
patients with complicated cataract
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this study will be to evaluate the pharmacokinetics of single and <br/ ><br>multiple doses of topical Posaconazole eye drop in human eye.Timepoint: aqueous and tear fluid analysis after 1 hour of last drop of posaconazole instillation
- Secondary Outcome Measures
Name Time Method To compare the ocular penetration and aqueous concentration of single dose and multi dose <br/ ><br>application of 1% concentration of topical Posaconazole eye drop.Timepoint: after 1 hour of last drop instillation