Effects of Low-Intensity Blood Flow Restriction Training in Normoxia and Hypoxia Conditions
- Conditions
- Hypoxia, AltitudeBlood Flow RestrictionResistance Training
- Interventions
- Other: high-intensity resistance trainingOther: low-intensity resistance training combined with blood flow restrictionOther: low-intensity resistance training in hypoxia conditionOther: low-intensity resistance trainingOther: low-intensity resistance training combined with blood flow restriction in hypoxia condition
- Registration Number
- NCT06171841
- Lead Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
- Brief Summary
One approach to significantly reducing resistance training intensity while maintaining effectiveness in muscle mass and strength development involves conducting training sessions under hypoxic conditions. This is likely due to heightened physiological responses. While sports science research indicates a substantial impact of hypoxic conditions on immediate increases in metabolic stress and augmented hormonal responses, recent findings suggest that the role of their influence on skeletal muscle adaptations post-resistance training under hypoxic conditions remains unknown. Additionally, there is a lack of reports on whether the type of hypoxia applied via blood flow restriction or chamber differentiates the increase in secretion of these catecholamines in both immediate and long-term aspects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Regularly physically active (at least 30 mins of structured exercise 3 times per week),
- Sea-level natives,
- Experienced in resistance training (at least one year of experience in regular resistance exercise)
- presence of any medical risk factors to exercise and/or exposure to altitude
- presence of any medical condition that would make the protocol unreasonably hazardous for the participant
- smokers
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description High-Intensity Normoxia high-intensity resistance training Participants will be breathing room air, and perform high-intensity lower-body resistance exercise. Low-Intensity Normoxia with Blood Flow Restriction low-intensity resistance training combined with blood flow restriction Participants will be breathing room air, and perform low-intensity lower-body resistance exercise combined with blood flow restriction. Low-Intensity Hypoxia low-intensity resistance training in hypoxia condition Participants will be breathing a 13% oxygen gas mixture, and perform low-intensity lower-body resistance exercise. Low-Intensity Normoxia low-intensity resistance training Participants will be breathing room air, and perform low-intensity lower-body resistance exercise. Low-Intensity Hypoxia with Blood Flow Restriction low-intensity resistance training combined with blood flow restriction in hypoxia condition Participants will be breathing a 13% oxygen gas mixture, and perform low-intensity lower-body resistance exercise combined with blood flow restriction.
- Primary Outcome Measures
Name Time Method Countermovement Jump Height Immediately pre and post first and last training session Countermovement jump height will be performed estimated via take-off velocity performed on force plates to Participants will perform 3 trials on force plate.
Catecholamine Response Immediately pre and post first and last training session A blood sample will be analyzed to quantify changes in epinephrine and norepinephrine level changes.
Force Output Immediately pre and post first and last training session Force plate will be used to quantify maximum absolute (N) and relative force output (body mass divided per force output in N/kg) during maximum voluntary isometric back squat in a 100ms time frame. Participants will be pushing as hard and as fast as they can on an unmoveable barbell while standing on a force plate.
One-Repetition Maximum within 5 days from the start and end of training One-Repetition Maximum test in leg press exercise will be performed to quantify maximum lower body dynamic strength (kg). Participants will be performing single repetitions of leg press exercise with increasing load until volitional failure.
Countermovement Jump Power Output Immediately pre and post first and last training session Countermovement jump performance will be performed to quantify maximum lower body relative and absolute power-output (W/kg and W), and jump height (cm) with concomitant assessment of contraction depth (cm) and contraction time (ms). Participants will perform 3 trials on force plate.
Maximum Number of Repetitions within 5 days from the start and end of training A maximum number of repetitions in leg press exercise will be performed to quantify lower body strength endurance (number). Participants will be performing leg press exercise at 50% of one-repetition maximum until volitional failure.
Muscle Thickness within 5 days from the start and end of training Ultrasonography measure will be used to quantify changes in vastus medialis oblique cross-sectional area.
Muscle Stiffness Immediately pre and post first and last training session Myotonometry measure will be used to quantify changes in vastus medialis oblique muscle stiffness in N/m
- Secondary Outcome Measures
Name Time Method Perception of Pain Immediately pre and post every training session A visual analogue scale will be used to quantify the perception of pain (units on a scale).
Perception of Effort Immediately pre and post every training session The rate of perceived exertion scale will be used to quantify the perception of effort (units on a scale).
Blood Pressure Immediately pre and post first and last training session Systolic and diastolic blood pressure will be measured to quantify blood pressure responses.
Trial Locations
- Locations (1)
The Jerzy Kukuczka Academy of Physical Education
🇵🇱Katowice, Śląsk, Poland