Macrophage Migration Inhibitory Factor for Diagnosing Endometriosis and Its Severity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 主要终点
- level of serum macrophage migration inhibitory factor and stage of the disease
研究概览
简要总结
Endometriosis is a chronic disease affecting women of reproductive age. Macrophage migration inhibitory factor (MIF) is one of non-invasive blood biomarker that was detected in sera of endometriotic patients.The aim of this study was to evaluate the value of serum macrophage migration inhibitory factor in diagnosing endometriosis in women with infertility and chronic pelvic pain and correlate its level with the stage of the disease. Three hundred patient candidate for diagnostic laparoscopy were included in a case-control observational study
详细描述
observational case-control study conducted in Fayoum University hospital from March 2016 till September 2018. Three hundred women candidate for diagnostic laparoscopy for either infertility or gynecologic chronic pelvic pain were included. The study group included patients with diagnostic criteria of endometriosis. The control group included other causes of infertility or pelvic pain.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •postmenstrual women
- •in childbearing period,
- •presenting with either gynecologic chronic pelvic pain (CPP) or infertility
- •indicated and fit for diagnostic laparoscopy.
- •All women must have no hormonal treatment for the last 3 months and.
排除标准
- •Women with bleeding tendency,
- •suspicious of gynecologic malignancy or
- •active infection
结局指标
主要结局
level of serum macrophage migration inhibitory factor and stage of the disease
时间窗: one year
serum MIF is a promising marker for noninvasive diagnosis of severity of endometriosis
次要结局
未报告次要终点
研究者
Sahar MY Elbaradie
associate Professor
Fayoum University Hospital